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2013 1
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Page 1
TBX2 acts as a potent transcriptional silencer of tumour suppressor genes through interaction with the CoREST complex to sustain the proliferation of breast cancers.
McIntyre AJ, Angel CZ, Smith JS, Templeman A, Beattie K, Beattie S, Ormrod A, Devlin E, McGreevy C, Bothwell C, Eddie SL, Buckley NE, Williams R, Mullan PB. McIntyre AJ, et al. Among authors: williams r. Nucleic Acids Res. 2022 Jun 24;50(11):6154-6173. doi: 10.1093/nar/gkac494. Nucleic Acids Res. 2022. PMID: 35687133 Free PMC article.
Identification and SAR exploration of a novel series of Legumain inhibitors.
Eddie SL, Gregson A, Graham E, Burton S, Harrison T, Burden R, Scott CJ, Mullan PB, Williams R. Eddie SL, et al. Among authors: williams r. Bioorg Med Chem Lett. 2019 Jun 15;29(12):1546-1548. doi: 10.1016/j.bmcl.2019.03.019. Epub 2019 Mar 29. Bioorg Med Chem Lett. 2019. PMID: 31005445
P3 SAR exploration of biphenyl carbamate based Legumain inhibitors.
Higgins C, Bouazzaoui S, Gaddale K, D'Costa Z, Templeman A, O'Rourke M, Young A, Scott C, Harrison T, Mullan P, Williams R. Higgins C, et al. Among authors: williams r. Bioorg Med Chem Lett. 2014 Jun 1;24(11):2521-4. doi: 10.1016/j.bmcl.2014.04.002. Epub 2014 Apr 12. Bioorg Med Chem Lett. 2014. PMID: 24775305
Investigating Radiotherapy Response in a Novel Syngeneic Model of Prostate Cancer.
Haughey CM, Mukherjee D, Steele RE, Popple A, Dura-Perez L, Pickard A, Patel M, Jain S, Mullan PB, Williams R, Oliveira P, Buckley NE, Honeychurch J, S McDade S, Illidge T, Mills IG, Eddie SL. Haughey CM, et al. Among authors: williams r. Cancers (Basel). 2020 Sep 29;12(10):2804. doi: 10.3390/cancers12102804. Cancers (Basel). 2020. PMID: 33003551 Free PMC article.
16 results