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Second-Generation Dual FXR/sEH Modulators with Optimized Pharmacokinetics.
Helmstädter M, Kaiser A, Brunst S, Schmidt J, Ronchetti R, Weizel L, Proschak E, Merk D. Helmstädter M, et al. Among authors: ronchetti r. J Med Chem. 2021 Jul 8;64(13):9525-9536. doi: 10.1021/acs.jmedchem.1c00831. Epub 2021 Jun 24. J Med Chem. 2021. PMID: 34165993
Garcinoic Acid Is a Natural and Selective Agonist of Pregnane X Receptor.
Bartolini D, De Franco F, Torquato P, Marinelli R, Cerra B, Ronchetti R, Schon A, Fallarino F, De Luca A, Bellezza G, Ferri I, Sidoni A, Walton WG, Pellock SJ, Redinbo MR, Mani S, Pellicciari R, Gioiello A, Galli F. Bartolini D, et al. Among authors: ronchetti r. J Med Chem. 2020 Apr 9;63(7):3701-3712. doi: 10.1021/acs.jmedchem.0c00012. Epub 2020 Mar 20. J Med Chem. 2020. PMID: 32160459 Free PMC article.