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Showing results for retina alves
Your search for Rezina Alves retrieved no results
Structural and functional changes in the retina in Parkinson's disease.
Alves JN, Westner BU, Højlund A, Weil RS, Dalal SS. Alves JN, et al. J Neurol Neurosurg Psychiatry. 2023 Jun;94(6):448-456. doi: 10.1136/jnnp-2022-329342. Epub 2023 Feb 17. J Neurol Neurosurg Psychiatry. 2023. PMID: 36806480 Free PMC article. Review.
We review the underlying chemical changes seen with loss of retinal dopaminergic neurons and the effect of levodopa treatment on the retina in Parkinson's disease. Finally, we consider whether retinal abnormalities in Parkinson's disease could have a role as potential mark …
We review the underlying chemical changes seen with loss of retinal dopaminergic neurons and the effect of levodopa treatment on the reti …
Microglial Cell Dysfunction in CRB1-Associated Retinopathies.
Alves CH, Wijnholds J. Alves CH, et al. Adv Exp Med Biol. 2019;1185:159-163. doi: 10.1007/978-3-030-27378-1_26. Adv Exp Med Biol. 2019. PMID: 31884605 Review.
Among these people, approximately 80,000 are or will become blind in their first decades of life due to mutations in both alleles of the Crumbs homologue-1 (CRB1) gene. Microglia are the resident immune surveyor cells in the retina, and their roles have been heavily studie …
Among these people, approximately 80,000 are or will become blind in their first decades of life due to mutations in both alleles of the Cru …
Microglia Contribution to the Regulation of the Retinal and Choroidal Vasculature in Age-Related Macular Degeneration.
Alves CH, Fernandes R, Santiago AR, Ambrósio AF. Alves CH, et al. Cells. 2020 May 14;9(5):1217. doi: 10.3390/cells9051217. Cells. 2020. PMID: 32423062 Free PMC article. Review.
The retina is a highly metabolically active tissue with high-level consumption of nutrients and oxygen. This high metabolic demand requires a properly developed and maintained vascular system. The retina is nourished by two systems: the central retinal artery that s …
The retina is a highly metabolically active tissue with high-level consumption of nutrients and oxygen. This high metabolic demand re …
Retina and Choroid of Diabetic Patients Without Observed Retinal Vascular Changes: A Longitudinal Study.
Tavares Ferreira J, Proença R, Alves M, Dias-Santos A, Santos BO, Cunha JP, Papoila AL, Abegão Pinto L. Tavares Ferreira J, et al. Am J Ophthalmol. 2017 Apr;176:15-25. doi: 10.1016/j.ajo.2016.12.023. Epub 2017 Jan 2. Am J Ophthalmol. 2017. PMID: 28057456 Free article.
CONCLUSIONS: Diabetic patients without DR showed a thicker choroid and a thinner retina, particularly in inner layers, after 1 year of follow-up. These structural changes may correspond to the early neurodegenerative phase of DR....
CONCLUSIONS: Diabetic patients without DR showed a thicker choroid and a thinner retina, particularly in inner layers, after 1 year o …
Melanopsin System Dysfunction in Smith-Magenis Syndrome Patients.
Barboni MTS, Bueno C, Nagy BV, Maia PL, Vidal KSM, Alves RC, Reiter RJ, do Amaral FG, Cipolla-Neto J, Ventura DF. Barboni MTS, et al. Invest Ophthalmol Vis Sci. 2018 Jan 1;59(1):362-369. doi: 10.1167/iovs.17-22612. Invest Ophthalmol Vis Sci. 2018. PMID: 29346496
The CRB1 and adherens junction complex proteins in retinal development and maintenance.
Alves CH, Pellissier LP, Wijnholds J. Alves CH, et al. Prog Retin Eye Res. 2014 May;40:35-52. doi: 10.1016/j.preteyeres.2014.01.001. Epub 2014 Feb 6. Prog Retin Eye Res. 2014. PMID: 24508727 Review.
The knowledge acquired from the different mutant animals for these proteins corroborate their importance in retina development and maintenance of normal retinal structure and function. More recently, several studies have tried to unravel the connection between the apical p …
The knowledge acquired from the different mutant animals for these proteins corroborate their importance in retina development and ma …
CRB2 in immature photoreceptors determines the superior-inferior symmetry of the developing retina to maintain retinal structure and function.
Quinn PM, Alves CH, Klooster J, Wijnholds J. Quinn PM, et al. Hum Mol Genet. 2018 Sep 15;27(18):3137-3153. doi: 10.1093/hmg/ddy194. Hum Mol Genet. 2018. PMID: 29893966
Previously, we showed that Crb1 knockout mice developed a slow-progressing retinal phenotype at foci in the inferior retina, although specific ablation of Crb2 in immature photoreceptors leads to an early-onset phenotype throughout the retina. ...Our data showed tha …
Previously, we showed that Crb1 knockout mice developed a slow-progressing retinal phenotype at foci in the inferior retina, although …
AAV Gene Augmentation Therapy for CRB1-Associated Retinitis Pigmentosa.
Alves CH, Wijnholds J. Alves CH, et al. Methods Mol Biol. 2018;1715:135-151. doi: 10.1007/978-1-4939-7522-8_10. Methods Mol Biol. 2018. PMID: 29188511
In this chapter we describe a technique to deliver AAV vectors, into the murine retinas, via the subretinal route. We also present protocols to detect expression of the therapeutic protein by fluorescence immunohistochemistry and to perform histological studies using ultra …
In this chapter we describe a technique to deliver AAV vectors, into the murine retinas, via the subretinal route. We also present pr …
83 results