Rene Van Elk - Search Results

Year	Number of Results
2004	1
2005	2
2006	1
2007	1
2009	1
2010	3
2011	5
2012	5
2013	2
2014	1
2015	1
2024	0

1

Structural basis of ligand recognition in 5-HT3 receptors.

Kesters D, Thompson AJ, Brams M, van Elk R, Spurny R, Geitmann M, Villalgordo JM, Guskov A, Danielson UH, Lummis SC, Smit AB, Ulens C. Kesters D, et al. Among authors: van elk r. EMBO Rep. 2013 Jan;14(1):49-56. doi: 10.1038/embor.2012.189. Epub 2012 Nov 30. EMBO Rep. 2013. PMID: 23196367 Free PMC article.

2

Assembly of a π-π stack of ligands in the binding site of an acetylcholine-binding protein.

Stornaiuolo M, De Kloe GE, Rucktooa P, Fish A, van Elk R, Edink ES, Bertrand D, Smit AB, de Esch IJ, Sixma TK. Stornaiuolo M, et al. Among authors: van elk r. Nat Commun. 2013;4:1875. doi: 10.1038/ncomms2900. Nat Commun. 2013. PMID: 23695669 Free PMC article.

3

Fragment growing induces conformational changes in acetylcholine-binding protein: a structural and thermodynamic analysis.

Edink E, Rucktooa P, Retra K, Akdemir A, Nahar T, Zuiderveld O, van Elk R, Janssen E, van Nierop P, van Muijlwijk-Koezen J, Smit AB, Sixma TK, Leurs R, de Esch IJ. Edink E, et al. Among authors: van elk r. J Am Chem Soc. 2011 Apr 13;133(14):5363-71. doi: 10.1021/ja110571r. Epub 2011 Feb 15. J Am Chem Soc. 2011. PMID: 21322593

4

Crystal structures of a cysteine-modified mutant in loop D of acetylcholine-binding protein.

Brams M, Gay EA, Sáez JC, Guskov A, van Elk R, van der Schors RC, Peigneur S, Tytgat J, Strelkov SV, Smit AB, Yakel JL, Ulens C. Brams M, et al. Among authors: van elk r. J Biol Chem. 2011 Feb 11;286(6):4420-8. doi: 10.1074/jbc.M110.188730. Epub 2010 Nov 29. J Biol Chem. 2011. PMID: 21115477 Free PMC article.

5

Structure-based design, synthesis and structure-activity relationships of dibenzosuberyl- and benzoate-substituted tropines as ligands for acetylcholine-binding protein.

Edink E, Akdemir A, Jansen C, van Elk R, Zuiderveld O, de Kanter FJ, van Muijlwijk-Koezen JE, Smit AB, Leurs R, de Esch IJ. Edink E, et al. Among authors: van elk r. Bioorg Med Chem Lett. 2012 Feb 1;22(3):1448-54. doi: 10.1016/j.bmcl.2011.12.008. Epub 2011 Dec 9. Bioorg Med Chem Lett. 2012. PMID: 22243960

6

AChBP-targeted alpha-conotoxin correlates distinct binding orientations with nAChR subtype selectivity.

Dutertre S, Ulens C, Büttner R, Fish A, van Elk R, Kendel Y, Hopping G, Alewood PF, Schroeder C, Nicke A, Smit AB, Sixma TK, Lewis RJ. Dutertre S, et al. Among authors: van elk r. EMBO J. 2007 Aug 22;26(16):3858-67. doi: 10.1038/sj.emboj.7601785. Epub 2007 Jul 26. EMBO J. 2007. PMID: 17660751 Free PMC article.

7

A structural and mutagenic blueprint for molecular recognition of strychnine and d-tubocurarine by different cys-loop receptors.

Brams M, Pandya A, Kuzmin D, van Elk R, Krijnen L, Yakel JL, Tsetlin V, Smit AB, Ulens C. Brams M, et al. Among authors: van elk r. PLoS Biol. 2011 Mar;9(3):e1001034. doi: 10.1371/journal.pbio.1001034. Epub 2011 Mar 29. PLoS Biol. 2011. PMID: 21468359 Free PMC article.

8

Crystal structure of nicotinic acetylcholine receptor homolog AChBP in complex with an alpha-conotoxin PnIA variant.

Celie PH, Kasheverov IE, Mordvintsev DY, Hogg RC, van Nierop P, van Elk R, van Rossum-Fikkert SE, Zhmak MN, Bertrand D, Tsetlin V, Sixma TK, Smit AB. Celie PH, et al. Among authors: van elk r. Nat Struct Mol Biol. 2005 Jul;12(7):582-8. doi: 10.1038/nsmb951. Epub 2005 Jun 12. Nat Struct Mol Biol. 2005. PMID: 15951818

9

Development of Plate Reader and On-Line Microfluidic Screening to Identify Ligands of the 5-Hydroxytryptamine Binding Protein in Venoms.

Otvos RA, Iyer JK, van Elk R, Ulens C, Niessen WM, Somsen GW, Kini RM, Smit AB, Kool J. Otvos RA, et al. Among authors: van elk r. Toxins (Basel). 2015 Jun 24;7(7):2336-53. doi: 10.3390/toxins7072336. Toxins (Basel). 2015. PMID: 26114334 Free PMC article.

10

Structural characterization of binding mode of smoking cessation drugs to nicotinic acetylcholine receptors through study of ligand complexes with acetylcholine-binding protein.

Rucktooa P, Haseler CA, van Elk R, Smit AB, Gallagher T, Sixma TK. Rucktooa P, et al. Among authors: van elk r. J Biol Chem. 2012 Jul 6;287(28):23283-93. doi: 10.1074/jbc.M112.360347. Epub 2012 May 2. J Biol Chem. 2012. PMID: 22553201 Free PMC article.

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