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Page 1
Nature-inspired enzymatic cascades to build valuable compounds.
Biotechnol Adv. 2015 Sep-Oct;33(5):394-411. doi: 10.1016/j.biotechadv.2015.03.010. Epub 2015 Mar 18.
Biotechnol Adv. 2015.
PMID: 25795056
Review.
Nonlinear Biosynthetic Assembly of Alpiniamide by a Hybrid cis/trans-AT PKS-NRPS.
Sigrist R, Luhavaya H, McKinnie SMK, Ferreira da Silva A, Jurberg ID, Moore BS, Gonzaga de Oliveira L.
Sigrist R, et al.
ACS Chem Biol. 2020 Apr 17;15(4):1067-1077. doi: 10.1021/acschembio.0c00081. Epub 2020 Apr 6.
ACS Chem Biol. 2020.
PMID: 32195572
Free PMC article.
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Production of Epoxyketone Peptide-Based Proteasome Inhibitors by Streptomyces sp. BRA-346: Regulation and Biosynthesis.
Domingues Vieira B, Niero H, de Felício R, Giolo Alves LF, Freitas Bazzano C, Sigrist R, Costa Furtado L, Felix Persinoti G, Veras Costa-Lotufo L, Barretto Barbosa Trivella D.
Domingues Vieira B, et al. Among authors: sigrist r.
Front Microbiol. 2022 Mar 24;13:786008. doi: 10.3389/fmicb.2022.786008. eCollection 2022.
Front Microbiol. 2022.
PMID: 35401454
Free PMC article.
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Mass Spectrometry-Guided Genome Mining as a Tool to Uncover Novel Natural Products.
Sigrist R, Paulo BS, Angolini CFF, De Oliveira LG.
Sigrist R, et al.
J Vis Exp. 2020 Mar 12;(157). doi: 10.3791/60825.
J Vis Exp. 2020.
PMID: 32225138
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Biosynthesis of l-4-Chlorokynurenine, an Antidepressant Prodrug and a Non-Proteinogenic Amino Acid Found in Lipopeptide Antibiotics.
Luhavaya H, Sigrist R, Chekan JR, McKinnie SMK, Moore BS.
Luhavaya H, et al. Among authors: sigrist r.
Angew Chem Int Ed Engl. 2019 Jun 17;58(25):8394-8399. doi: 10.1002/anie.201901571. Epub 2019 May 13.
Angew Chem Int Ed Engl. 2019.
PMID: 30963655
Free PMC article.
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Chemical Elicitors Induce Rare Bioactive Secondary Metabolites in Deep-Sea Bacteria under Laboratory Conditions.
de Felício R, Ballone P, Bazzano CF, Alves LFG, Sigrist R, Infante GP, Niero H, Rodrigues-Costa F, Fernandes AZN, Tonon LAC, Paradela LS, Costa RKE, Dias SMG, Dessen A, Telles GP, da Silva MAC, Lima AOS, Trivella DBB.
de Felício R, et al. Among authors: sigrist r.
Metabolites. 2021 Feb 12;11(2):107. doi: 10.3390/metabo11020107.
Metabolites. 2021.
PMID: 33673148
Free PMC article.
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Whole-Genome Sequence of the Endophytic Streptomyces sp. Strain CBMAI 2042, Isolated from Citrus sinensis.
Gonzaga de Oliveira L, Sigrist R, Sachetto Paulo B, Samborskyy M.
Gonzaga de Oliveira L, et al. Among authors: sigrist r.
Microbiol Resour Announc. 2019 Jan 10;8(2):e01426-18. doi: 10.1128/MRA.01426-18. eCollection 2019 Jan.
Microbiol Resour Announc. 2019.
PMID: 30643884
Free PMC article.
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