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Year Number of Results
1957 1
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1969 1
1974 1
1975 4
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1977 6
1978 8
1979 9
1980 8
1981 14
1982 18
1983 20
1984 18
1985 34
1986 37
1987 46
1988 71
1989 81
1990 118
1991 140
1992 179
1993 221
1994 308
1995 307
1996 404
1997 457
1998 528
1999 619
2000 709
2001 773
2002 794
2003 995
2004 1121
2005 1253
2006 1356
2007 1416
2008 1534
2009 1663
2010 1878
2011 2001
2012 2255
2013 2415
2014 2584
2015 2552
2016 2496
2017 2445
2018 2494
2019 2526
2020 2785
2021 2774
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2023 2680
2024 1395

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46,266 results

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Page 1
Showing results for gene link
Your search for René Klink retrieved no results
Gene essentiality and variability: What is the link? A within- and between-species perspective.
Dubois-Mignon T, Monget P. Dubois-Mignon T, et al. Bioessays. 2022 Nov;44(11):e2200132. doi: 10.1002/bies.202200132. Epub 2022 Sep 23. Bioessays. 2022. PMID: 36148844 Review.
However, the link between the essentiality of a gene and its degree of polymorphism is unclear. ...Then we show that the environment can induce adaptation of species by rapidly evolving genes. We also study the role of positive selection on speciation, partic …
However, the link between the essentiality of a gene and its degree of polymorphism is unclear. ...Then we show that the envir …
The intriguing complexities of mammalian gene regulation: how to link enhancers to regulated genes. Are we there yet?
Daniel B, Nagy G, Nagy L. Daniel B, et al. FEBS Lett. 2014 Aug 1;588(15):2379-91. doi: 10.1016/j.febslet.2014.05.041. Epub 2014 Jun 16. FEBS Lett. 2014. PMID: 24945732 Free article. Review.
However, these cis-acting elements are often located very far away from the regulated gene. Therefore, it is hard to find all of them and link them to the regulated gene. An intriguing and unresolved issue of the field is to identify all of the enhancers of a …
However, these cis-acting elements are often located very far away from the regulated gene. Therefore, it is hard to find all of them …
Enhancer-gene specificity in development and disease.
Pachano T, Haro E, Rada-Iglesias A. Pachano T, et al. Development. 2022 Jun 1;149(11):dev186536. doi: 10.1242/dev.186536. Epub 2022 Jun 10. Development. 2022. PMID: 35686641 Free PMC article. Review.
Enhancers control the establishment of spatiotemporal gene expression patterns throughout development. Over the past decade, the development of new technologies has improved our capacity to link enhancers with their target genes based on their colocalization …
Enhancers control the establishment of spatiotemporal gene expression patterns throughout development. Over the past decade, the deve …
Synthetic gene circuits as tools for drug discovery.
Beitz AM, Oakes CG, Galloway KE. Beitz AM, et al. Trends Biotechnol. 2022 Feb;40(2):210-225. doi: 10.1016/j.tibtech.2021.06.007. Epub 2021 Aug 4. Trends Biotechnol. 2022. PMID: 34364685 Review.
Within mammalian systems, there exists enormous opportunity to use synthetic gene circuits to enhance phenotype-based drug discovery, to map the molecular origins of disease, and to validate therapeutics in complex cellular systems. ...By tracking events and cellular state …
Within mammalian systems, there exists enormous opportunity to use synthetic gene circuits to enhance phenotype-based drug discovery, …
"Genes".
Prohaska SJ, Stadler PF. Prohaska SJ, et al. Theory Biosci. 2008 Aug;127(3):215-21. doi: 10.1007/s12064-008-0025-0. Epub 2008 Mar 5. Theory Biosci. 2008. PMID: 18320253 Free PMC article.
The downside of the resulting high resolution is that it becomes very tedious to address features on the organismal and phenotypic levels with a language based on molecular terms. Looking for the missing link between biological disciplines dealing with different levels of …
The downside of the resulting high resolution is that it becomes very tedious to address features on the organismal and phenotypic levels wi …
Gene body methylation is under selection in Arabidopsis thaliana.
Muyle A, Ross-Ibarra J, Seymour DK, Gaut BS. Muyle A, et al. Genetics. 2021 Jun 24;218(2):iyab061. doi: 10.1093/genetics/iyab061. Genetics. 2021. PMID: 33871638 Free PMC article.
In plants, mammals and insects, some genes are methylated in the CG dinucleotide context, a phenomenon called gene body methylation (gbM). ...Finally, we investigated the potential function of gbM through its link with gene expression. Across genes
In plants, mammals and insects, some genes are methylated in the CG dinucleotide context, a phenomenon called gene body methyl …
Relevance and mechanisms of transvection.
Galouzis CC, Prud'homme B. Galouzis CC, et al. C R Biol. 2021 Dec 20;344(4):373-387. doi: 10.5802/crbiol.69. C R Biol. 2021. PMID: 35787607 Free article. Review.
Transvection, the functional interaction between homologous alleles, was first described in Drosophila in the 1950's. While transvection has been documented in a growing list of genes, using mutant alleles or synthetic constructs, in Drosophila and other organisms, the ext …
Transvection, the functional interaction between homologous alleles, was first described in Drosophila in the 1950's. While transvection has …
Characterization of the promoter for the rat and human link protein gene.
Rhodes C, Savagner P, Line S, Sasaki M, Chirigos M, Doege K, Yamada Y. Rhodes C, et al. Nucleic Acids Res. 1991 Apr 25;19(8):1933-9. doi: 10.1093/nar/19.8.1933. Nucleic Acids Res. 1991. PMID: 2030970 Free PMC article.
Several overlapping clones were isolated for the human link protein gene, while only one clone was obtained for the rat. ...Transcriptional initiation sites for the human link gene were determined by specific primer extension of RNA from human fetal ca …
Several overlapping clones were isolated for the human link protein gene, while only one clone was obtained for the rat. ...Tr …
The integrative biology of genetic dominance.
Billiard S, Castric V, Llaurens V. Billiard S, et al. Biol Rev Camb Philos Soc. 2021 Dec;96(6):2925-2942. doi: 10.1111/brv.12786. Epub 2021 Aug 12. Biol Rev Camb Philos Soc. 2021. PMID: 34382317 Free PMC article. Review.
Dominance is a basic property of inheritance systems describing the link between a diploid genotype at a single locus and the resulting phenotype. ...Recent theoretical and empirical advances however suggest that these opposing views can be reconciled, notably using models …
Dominance is a basic property of inheritance systems describing the link between a diploid genotype at a single locus and the resulti …
46,266 results
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