Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1957 1
1965 1
1967 2
1969 1
1974 1
1975 4
1976 4
1977 6
1978 8
1979 9
1980 8
1981 14
1982 18
1983 20
1984 18
1985 34
1986 37
1987 46
1988 71
1989 81
1990 118
1991 140
1992 179
1993 221
1994 308
1995 307
1996 404
1997 457
1998 528
1999 619
2000 709
2001 773
2002 794
2003 995
2004 1121
2005 1253
2006 1356
2007 1416
2008 1534
2009 1663
2010 1878
2011 2001
2012 2255
2013 2415
2014 2584
2015 2553
2016 2497
2017 2445
2018 2494
2019 2525
2020 2785
2021 2773
2022 2632
2023 2680
2024 1111

Text availability

Article attribute

Article type

Publication date

Search Results

45,994 results

Results by year

Filters applied: . Clear all
Page 1
Showing results for gene link
Your search for René Klink retrieved no results
Gene essentiality and variability: What is the link? A within- and between-species perspective.
Dubois-Mignon T, Monget P. Dubois-Mignon T, et al. Bioessays. 2022 Nov;44(11):e2200132. doi: 10.1002/bies.202200132. Epub 2022 Sep 23. Bioessays. 2022. PMID: 36148844 Review.
However, the link between the essentiality of a gene and its degree of polymorphism is unclear. ...Then we show that the environment can induce adaptation of species by rapidly evolving genes. We also study the role of positive selection on speciation, partic …
However, the link between the essentiality of a gene and its degree of polymorphism is unclear. ...Then we show that the envir …
The intriguing complexities of mammalian gene regulation: how to link enhancers to regulated genes. Are we there yet?
Daniel B, Nagy G, Nagy L. Daniel B, et al. FEBS Lett. 2014 Aug 1;588(15):2379-91. doi: 10.1016/j.febslet.2014.05.041. Epub 2014 Jun 16. FEBS Lett. 2014. PMID: 24945732 Free article. Review.
However, these cis-acting elements are often located very far away from the regulated gene. Therefore, it is hard to find all of them and link them to the regulated gene. An intriguing and unresolved issue of the field is to identify all of the enhancers of a …
However, these cis-acting elements are often located very far away from the regulated gene. Therefore, it is hard to find all of them …
Enhancer-gene specificity in development and disease.
Pachano T, Haro E, Rada-Iglesias A. Pachano T, et al. Development. 2022 Jun 1;149(11):dev186536. doi: 10.1242/dev.186536. Epub 2022 Jun 10. Development. 2022. PMID: 35686641 Free PMC article. Review.
Enhancers control the establishment of spatiotemporal gene expression patterns throughout development. Over the past decade, the development of new technologies has improved our capacity to link enhancers with their target genes based on their colocalization …
Enhancers control the establishment of spatiotemporal gene expression patterns throughout development. Over the past decade, the deve …
Synthetic gene circuits as tools for drug discovery.
Beitz AM, Oakes CG, Galloway KE. Beitz AM, et al. Trends Biotechnol. 2022 Feb;40(2):210-225. doi: 10.1016/j.tibtech.2021.06.007. Epub 2021 Aug 4. Trends Biotechnol. 2022. PMID: 34364685 Review.
Within mammalian systems, there exists enormous opportunity to use synthetic gene circuits to enhance phenotype-based drug discovery, to map the molecular origins of disease, and to validate therapeutics in complex cellular systems. ...By tracking events and cellular state …
Within mammalian systems, there exists enormous opportunity to use synthetic gene circuits to enhance phenotype-based drug discovery, …
Gene body methylation is under selection in Arabidopsis thaliana.
Muyle A, Ross-Ibarra J, Seymour DK, Gaut BS. Muyle A, et al. Genetics. 2021 Jun 24;218(2):iyab061. doi: 10.1093/genetics/iyab061. Genetics. 2021. PMID: 33871638 Free PMC article.
In plants, mammals and insects, some genes are methylated in the CG dinucleotide context, a phenomenon called gene body methylation (gbM). ...Finally, we investigated the potential function of gbM through its link with gene expression. Across genes …
In plants, mammals and insects, some genes are methylated in the CG dinucleotide context, a phenomenon called gene body methyl …
Relevance and mechanisms of transvection.
Galouzis CC, Prud'homme B. Galouzis CC, et al. C R Biol. 2021 Dec 20;344(4):373-387. doi: 10.5802/crbiol.69. C R Biol. 2021. PMID: 35787607 Free article. Review.
Transvection, the functional interaction between homologous alleles, was first described in Drosophila in the 1950's. While transvection has been documented in a growing list of genes, using mutant alleles or synthetic constructs, in Drosophila and other organisms, the ext …
Transvection, the functional interaction between homologous alleles, was first described in Drosophila in the 1950's. While transvection has …
Characterization of the promoter for the rat and human link protein gene.
Rhodes C, Savagner P, Line S, Sasaki M, Chirigos M, Doege K, Yamada Y. Rhodes C, et al. Nucleic Acids Res. 1991 Apr 25;19(8):1933-9. doi: 10.1093/nar/19.8.1933. Nucleic Acids Res. 1991. PMID: 2030970 Free PMC article.
Several overlapping clones were isolated for the human link protein gene, while only one clone was obtained for the rat. ...Transcriptional initiation sites for the human link gene were determined by specific primer extension of RNA from human fetal ca …
Several overlapping clones were isolated for the human link protein gene, while only one clone was obtained for the rat. ...Tr …
Chapter 15: disease gene prioritization.
Bromberg Y. Bromberg Y. PLoS Comput Biol. 2013 Apr;9(4):e1002902. doi: 10.1371/journal.pcbi.1002902. Epub 2013 Apr 25. PLoS Comput Biol. 2013. PMID: 23633938 Free PMC article.
Disease-causing aberrations in the normal function of a gene define that gene as a disease gene. Proving a causal link between a gene and a disease experimentally is expensive and time-consuming. ...Computational gene prioritization is ba …
Disease-causing aberrations in the normal function of a gene define that gene as a disease gene. Proving a causal li …
Systematic investigation of the homology sequences around the human fusion gene breakpoints in pan-cancer - bioinformatics study for a potential link to MMEJ.
Kim P, Kumar H, Yang C, Luo R, Liu J, Zhou X. Kim P, et al. Brief Bioinform. 2023 Sep 20;24(5):bbad314. doi: 10.1093/bib/bbad314. Brief Bioinform. 2023. PMID: 37635381 Free PMC article.
In this study, we systematically investigated the homology sequences around the genomic breakpoint area of human fusion genes, which were formed by the chromosomal rearrangements initiated by DNA double-strand breakage. Since the RNA-seq data is the typical data set to che …
In this study, we systematically investigated the homology sequences around the genomic breakpoint area of human fusion genes, which …
45,994 results
You have reached the last available page of results. Please see the User Guide for more information.