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Determination of critical quality attributes for monoclonal antibodies using quality by design principles.
Biologicals. 2016 Sep;44(5):291-305. doi: 10.1016/j.biologicals.2016.06.005. Epub 2016 Jul 25.
Biologicals. 2016.
PMID: 27461239
Review.
Challenges and Strategies for a Thorough Characterization of Antibody Acidic Charge Variants.
Liu YD, Cadang L, Bol K, Pan X, Tschudi K, Jazayri M, Camperi J, Michels D, Stults J, Harris RJ, Yang F.
Liu YD, et al. Among authors: harris rj.
Bioengineering (Basel). 2022 Nov 3;9(11):641. doi: 10.3390/bioengineering9110641.
Bioengineering (Basel). 2022.
PMID: 36354552
Free PMC article.
Item in Clipboard
Non-enzymatic hinge region fragmentation of antibodies in solution.
Cordoba AJ, Shyong BJ, Breen D, Harris RJ.
Cordoba AJ, et al. Among authors: harris rj.
J Chromatogr B Analyt Technol Biomed Life Sci. 2005 Apr 25;818(2):115-21. doi: 10.1016/j.jchromb.2004.12.033.
J Chromatogr B Analyt Technol Biomed Life Sci. 2005.
PMID: 15734150
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A sensitive mutation screening method supporting cell line development for biotherapeutics.
Valisheva I, Harris RJ, Zhu-Shimoni J.
Valisheva I, et al. Among authors: harris rj.
Anal Biochem. 2016 Jul 15;505:73-5. doi: 10.1016/j.ab.2016.04.007. Epub 2016 Apr 20.
Anal Biochem. 2016.
PMID: 27108188
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Effect of copper sulfate on performance of a serum-free CHO cell culture process and the level of free thiol in the recombinant antibody expressed.
Chaderjian WB, Chin ET, Harris RJ, Etcheverry TM.
Chaderjian WB, et al. Among authors: harris rj.
Biotechnol Prog. 2005 Mar-Apr;21(2):550-3. doi: 10.1021/bp0497029.
Biotechnol Prog. 2005.
PMID: 15801797
Item in Clipboard
Characterization of oligosaccharides in recombinant tissue plasminogen activator produced in Chinese hamster ovary cells: two decades of analytical technology development.
Borisov OV, Field M, Ling VT, Harris RJ.
Borisov OV, et al. Among authors: harris rj.
Anal Chem. 2009 Dec 1;81(23):9744-54. doi: 10.1021/ac901498k.
Anal Chem. 2009.
PMID: 19947664
Item in Clipboard
Charge variants in IgG1: Isolation, characterization, in vitro binding properties and pharmacokinetics in rats.
Khawli LA, Goswami S, Hutchinson R, Kwong ZW, Yang J, Wang X, Yao Z, Sreedhara A, Cano T, Tesar D, Nijem I, Allison DE, Wong PY, Kao YH, Quan C, Joshi A, Harris RJ, Motchnik P.
Khawli LA, et al. Among authors: harris rj.
MAbs. 2010 Nov-Dec;2(6):613-24. doi: 10.4161/mabs.2.6.13333. Epub 2010 Nov 1.
MAbs. 2010.
PMID: 20818176
Free PMC article.
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