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Novel benzimidazole-linked (thio)barbiturates as non-hydroxamate HDAC6 inhibitors targeting leukemia: Design, synthesis, and structure-activity relationship.
Arch Pharm (Weinheim). 2023 Jun;356(6):e2200433. doi: 10.1002/ardp.202200433. Epub 2023 Mar 21.
Arch Pharm (Weinheim). 2023.
PMID: 36942938
Neuroprotective Effects of Phytochemicals against Aluminum Chloride-Induced Alzheimer's Disease through ApoE4/LRP1, Wnt3/β-Catenin/GSK3β, and TLR4/NLRP3 Pathways with Physical and Mental Activities in a Rat Model.
Hamdan AME, Alharthi FHJ, Alanazi AH, El-Emam SZ, Zaghlool SS, Metwally K, Albalawi SA, Abdu YS, Mansour RE, Salem HA, Abd Elmageed ZY, Abu-Elfotuh K.
Hamdan AME, et al. Among authors: mansour re.
Pharmaceuticals (Basel). 2022 Aug 17;15(8):1008. doi: 10.3390/ph15081008.
Pharmaceuticals (Basel). 2022.
PMID: 36015156
Free PMC article.
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Discovery of novel benzimidazole derivatives as potent HDACs inhibitors against leukemia with (Thio)Hydantoin as zinc-binding moiety: Design, synthesis, enzyme inhibition, and cellular mechanistic study.
Abdulwahab HG, Mansour RE, Farghaly TA, El-Sehrawi HM.
Abdulwahab HG, et al. Among authors: mansour re.
Bioorg Chem. 2024 May;146:107284. doi: 10.1016/j.bioorg.2024.107284. Epub 2024 Mar 13.
Bioorg Chem. 2024.
PMID: 38493640
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