Reda G. Yousef - Search Results

Year	Number of Results
2021	2
2022	9
2023	13
2024	1

1

Anticancer derivative of the natural alkaloid, theobromine, inhibiting EGFR protein: Computer-aided drug discovery approach.

Eissa IH, Yousef RG, Elkaeed EB, Alsfouk AA, Husein DZ, Ibrahim IM, Alesawy MS, Elkady H, Metwaly AM. Eissa IH, et al. Among authors: yousef rg. PLoS One. 2023 Mar 9;18(3):e0282586. doi: 10.1371/journal.pone.0282586. eCollection 2023. PLoS One. 2023. PMID: 36893122 Free PMC article.

2

A Theobromine Derivative with Anticancer Properties Targeting VEGFR-2: Semisynthesis, in silico and in vitro Studies.

Eissa IH, Yousef RG, Elkady H, Elkaeed EB, Alsfouk AA, Husein DZ, Ibrahim IM, Radwan MM, Metwaly AM. Eissa IH, et al. Among authors: yousef rg. ChemistryOpen. 2023 Oct;12(10):e202300066. doi: 10.1002/open.202300066. ChemistryOpen. 2023. PMID: 37803417 Free PMC article.

3

New quinoxalin-2(1H)-one-derived VEGFR-2 inhibitors: Design, synthesis, in vitro anticancer evaluations, in silico ADMET, and docking studies.

El-Adl K, Sakr HM, Yousef RG, Mehany ABM, Abulkhair HS, Eissa IH. El-Adl K, et al. Among authors: yousef rg. Arch Pharm (Weinheim). 2022 Jul;355(7):e2200048. doi: 10.1002/ardp.202200048. Epub 2022 Apr 18. Arch Pharm (Weinheim). 2022. PMID: 35437829

4

New Anticancer Theobromine Derivative Targeting EGFR^WT and EGFR^T790M: Design, Semi-Synthesis, In Silico, and In Vitro Anticancer Studies.

Elkaeed EB, Yousef RG, Elkady H, Alsfouk AA, Husein DZ, Ibrahim IM, Metwaly AM, Eissa IH. Elkaeed EB, et al. Among authors: yousef rg. Molecules. 2022 Sep 9;27(18):5859. doi: 10.3390/molecules27185859. Molecules. 2022. PMID: 36144596 Free PMC article.

5

A New Anticancer Semisynthetic Theobromine Derivative Targeting EGFR Protein: CADDD Study.

Eissa IH, Yousef RG, Elkady H, Alsfouk AA, Alsfouk BA, Husein DZ, Ibrahim IM, Elkaeed EB, Metwaly AM. Eissa IH, et al. Among authors: yousef rg. Life (Basel). 2023 Jan 9;13(1):191. doi: 10.3390/life13010191. Life (Basel). 2023. PMID: 36676140 Free PMC article.

6

Discovery of New VEGFR-2 Inhibitors: Design, Synthesis, Anti-Proliferative Evaluation, Docking, and MD Simulation Studies.

Elkaeed EB, Yousef RG, Khalifa MM, Ibrahim A, Mehany ABM, Gobaara IMM, Alsfouk BA, Eldehna WM, Metwaly AM, Eissa IH, El-Zahabi MA. Elkaeed EB, et al. Among authors: yousef rg. Molecules. 2022 Sep 21;27(19):6203. doi: 10.3390/molecules27196203. Molecules. 2022. PMID: 36234734 Free PMC article.

7

(E)-N-(3-(1-(2-(4-(2,2,2-Trifluoroacetamido)benzoyl)hydrazono)ethyl)phenyl)nicotinamide: A Novel Pyridine Derivative for Inhibiting Vascular Endothelial Growth Factor Receptor-2: Synthesis, Computational, and Anticancer Studies.

Yousef RG, Elkady H, Elkaeed EB, Gobaara IMM, Al-Ghulikah HA, Husein DZ, Ibrahim IM, Metwaly AM, Eissa IH. Yousef RG, et al. Molecules. 2022 Nov 9;27(22):7719. doi: 10.3390/molecules27227719. Molecules. 2022. PMID: 36431818 Free PMC article.

8

Anti-cancer and immunomodulatory evaluation of new nicotinamide derivatives as potential VEGFR-2 inhibitors and apoptosis inducers: in vitro and in silico studies.

Yousef RG, Elwan A, Gobaara IMM, Mehany ABM, Eldehna WM, El-Metwally SA, A Alsfouk B, Elkaeed EB, Metwaly AM, Eissa IH. Yousef RG, et al. J Enzyme Inhib Med Chem. 2022 Dec;37(1):2206-2222. doi: 10.1080/14756366.2022.2110868. J Enzyme Inhib Med Chem. 2022. PMID: 35980113 Free PMC article.

9

Discovery of new nicotinamides as apoptotic VEGFR-2 inhibitors: virtual screening, synthesis, anti-proliferative, immunomodulatory, ADMET, toxicity, and molecular dynamic simulation studies.

Yousef RG, Ibrahim A, Khalifa MM, Eldehna WM, Gobaara IMM, Mehany ABM, Elkaeed EB, Alsfouk AA, Metwaly AM, Eissa IH. Yousef RG, et al. J Enzyme Inhib Med Chem. 2022 Dec;37(1):1389-1403. doi: 10.1080/14756366.2022.2070744. J Enzyme Inhib Med Chem. 2022. PMID: 35577416 Free PMC article.

10

In silico, in vitro VEGFR-2 inhibition, and anticancer activity of a 3-(hydrazonomethyl)naphthalene-2-ol derivative.

Elkaeed EB, Yousef RG, Elkady H, Mehany ABM, Alsfouk BA, Husein DZ, Ibrahim IM, Metwaly AM, Eissa IH. Elkaeed EB, et al. Among authors: yousef rg. J Biomol Struct Dyn. 2023 Sep-Oct;41(16):7986-8001. doi: 10.1080/07391102.2022.2127907. Epub 2022 Oct 2. J Biomol Struct Dyn. 2023. PMID: 36184591

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