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2008 1
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2014 3
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2023 3
2024 4

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Page 1
An oral SARS-CoV-2 Mpro inhibitor clinical candidate for the treatment of COVID-19.
Owen DR, Allerton CMN, Anderson AS, Aschenbrenner L, Avery M, Berritt S, Boras B, Cardin RD, Carlo A, Coffman KJ, Dantonio A, Di L, Eng H, Ferre R, Gajiwala KS, Gibson SA, Greasley SE, Hurst BL, Kadar EP, Kalgutkar AS, Lee JC, Lee J, Liu W, Mason SW, Noell S, Novak JJ, Obach RS, Ogilvie K, Patel NC, Pettersson M, Rai DK, Reese MR, Sammons MF, Sathish JG, Singh RSP, Steppan CM, Stewart AE, Tuttle JB, Updyke L, Verhoest PR, Wei L, Yang Q, Zhu Y. Owen DR, et al. Science. 2021 Dec 24;374(6575):1586-1593. doi: 10.1126/science.abl4784. Epub 2021 Nov 2. Science. 2021. PMID: 34726479 Free article.
Innovative Randomized Phase I Study and Dosing Regimen Selection to Accelerate and Inform Pivotal COVID-19 Trial of Nirmatrelvir.
Singh RSP, Toussi SS, Hackman F, Chan PL, Rao R, Allen R, Van Eyck L, Pawlak S, Kadar EP, Clark F, Shi H, Anderson AS, Binks M, Menon S, Nucci G, Bergman A. Singh RSP, et al. Clin Pharmacol Ther. 2022 Jul;112(1):101-111. doi: 10.1002/cpt.2603. Epub 2022 May 4. Clin Pharmacol Ther. 2022. PMID: 35388471 Free PMC article. Clinical Trial.
Nonlinear Protein Binding: Not What You Think.
Deitchman AN, Singh RSP, Derendorf H. Deitchman AN, et al. J Pharm Sci. 2018 Jul;107(7):1754-1760. doi: 10.1016/j.xphs.2018.03.023. Epub 2018 Apr 4. J Pharm Sci. 2018. PMID: 29626534 Free PMC article. Review.
Largazole pharmacokinetics in rats by LC-MS/MS.
Yu M, Salvador LA, Sy SK, Tang Y, Singh RS, Chen QY, Liu Y, Hong J, Derendorf H, Luesch H. Yu M, et al. Among authors: singh rs. Mar Drugs. 2014 Mar 20;12(3):1623-40. doi: 10.3390/md12031623. Mar Drugs. 2014. PMID: 24658499 Free PMC article.
37 results