Exploring New Tools for Risk Classification among Adults with Several Degrees of Obesity

Int J Environ Res Public Health. 2023 Jun 30;20(13):6263. doi: 10.3390/ijerph20136263.

Abstract

The epidemic of obesity worldwide has been recognized as a very important challenge. Within its complexity, the identification of higher-risk patients is essential, as it is unsustainable to offer access to treatment to all people with obesity. Several new approaches have recently been presented as important tools for risk stratification. In this research, we applied several of these tools in a cross-sectional study involving adults with obesity classes I, II, III, and super-obesity. The participants had their cardiometabolic risk profiles assessed. The study included adults with obesity aged 18 to 50 years (n = 404), who were evaluated using anthropometric, body composition, hemodynamic, physical fitness, and biochemical assessments. These variables were used to identify the prevalence of risk factors for cardiometabolic diseases according to the classes of obesity by gender and age group. The results showed high prevalence of risk factors, especially among the upper classes of obesity (BMI > 35 kg/m2) using single parameters as the waist circumference, with almost 90% above the cut-off point. For smaller numbers such as Glycated Hemoglobin, however, the prevalence was around 30%. Indexes such as the atherogenic index of plasma (AIP) had the highest prevalence, with 100% of the male participants identified as being at increased risk for cardiovascular disease.

Keywords: AIP; HOMA-IR; metabolic syndrome; obesity; risk assessment; risk stratification.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Body Mass Index
  • Cardiovascular Diseases* / etiology
  • Cross-Sectional Studies
  • Humans
  • Male
  • Metabolic Syndrome* / epidemiology
  • Obesity / complications
  • Risk Factors
  • Waist Circumference

Grants and funding

This research was funded by Effectiveness of a multidisciplinary program in the assessment of cardiometabolic risk factors and treatment of abdominal obesity in two municipalities in northwestern Paraná, funded by the Araucaria Foundation and the Ministry of Health through the public notice CP 01/2016 Research Program for the Unified Health System: Shared Management in Health—PPSUS 2015 Edition Araucaria Foundation-PR/SESA-PR/CNPq/MS-Decit and Coordination for the Improvement of Higher Education Personnel—CAPES Brazil for the Sandwich Doctorate Scholarship Abroad.