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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1985 1
1987 1
1989 1
1994 4
1997 1
1998 1
2000 2
2001 3
2002 3
2003 4
2004 1
2005 1
2006 1
2008 3
2009 1
2010 6
2011 8
2012 1
2013 4
2014 9
2015 10
2016 5
2017 3
2018 5
2019 10
2020 6
2021 12
2022 15
2023 11
2024 5

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120 results

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Page 1
Bruton's Tyrosine Kinase Inhibition in Multiple Sclerosis.
Schneider R, Oh J. Schneider R, et al. Curr Neurol Neurosci Rep. 2022 Nov;22(11):721-734. doi: 10.1007/s11910-022-01229-z. Epub 2022 Oct 27. Curr Neurol Neurosci Rep. 2022. PMID: 36301434 Free PMC article. Review.
RECENT FINDINGS: There is evidence that some BTKIs cross the blood-brain barrier and may be superior to currently available DMTs at dampening the chronic neuroinflammatory processes compartmentalized within the CNS that contribute to progressive worsening in people withMS …
RECENT FINDINGS: There is evidence that some BTKIs cross the blood-brain barrier and may be superior to currently available DMTs at d …
Current status of hepatocyte xenotransplantation.
Meier RPH, Navarro-Alvarez N, Morel P, Schuurman HJ, Strom S, Bühler LH. Meier RPH, et al. Int J Surg. 2015 Nov;23(Pt B):273-279. doi: 10.1016/j.ijsu.2015.08.077. Epub 2015 Sep 9. Int J Surg. 2015. PMID: 26361861 Free article. Review.
In this review we present an overview of the innate immune barriers in hepatocyte xenotransplantation, including the role of complement and natural antibodies; the role of phagocytic cells and ligands like CD47 in the regulation of phagocytic cells; and the role of Natural …
In this review we present an overview of the innate immune barriers in hepatocyte xenotransplantation, including the role of compleme …
Basement membrane stiffness determines metastases formation.
Reuten R, Zendehroud S, Nicolau M, Fleischhauer L, Laitala A, Kiderlen S, Nikodemus D, Wullkopf L, Nielsen SR, McNeilly S, Prein C, Rafaeva M, Schoof EM, Furtwängler B, Porse BT, Kim H, Won KJ, Sudhop S, Zornhagen KW, Suhr F, Maniati E, Pearce OMT, Koch M, Oddershede LB, Van Agtmael T, Madsen CD, Mayorca-Guiliani AE, Bloch W, Netz RR, Clausen-Schaumann H, Erler JT. Reuten R, et al. Nat Mater. 2021 Jun;20(6):892-903. doi: 10.1038/s41563-020-00894-0. Epub 2021 Jan 25. Nat Mater. 2021. PMID: 33495631 Free article.
The basement membrane (BM) is a special type of extracellular matrix and presents the major barrier cancer cells have to overcome multiple times to form metastases. ...Mechanistically, our biophysical and functional analyses in combination with mathematical simulations sho …
The basement membrane (BM) is a special type of extracellular matrix and presents the major barrier cancer cells have to overcome mul …
Recent advances in physical delivery enhancement of topical drugs.
Raphael AP, Wright OR, Benson HA, Prow TW. Raphael AP, et al. Curr Pharm Des. 2015;21(20):2830-47. doi: 10.2174/1381612821666150428144852. Curr Pharm Des. 2015. PMID: 25925114 Review.
Effective topical drug delivery into and/or through the skin is hindered by these epidermal barriers. A range of physical enhancement methods has been developed to selectively overcome this barrier. ...
Effective topical drug delivery into and/or through the skin is hindered by these epidermal barriers. A range of physical enhancement …
Implementing interventions to improve compassionate nursing care: A literature review.
Robinson J, Raphael D, Moeke-Maxwell T, Parr J, Gott M, Slark J. Robinson J, et al. Int Nurs Rev. 2023 Nov 17. doi: 10.1111/inr.12910. Online ahead of print. Int Nurs Rev. 2023. PMID: 37975578 Review.
Excessive workload, overly rigid reporting and organisational indifference are barriers to delivery of compassionate care. IMPLICATIONS FOR NURSING POLICY: Health policy is used to inform the systematic implementation and delivery of patient care informed by best evidence. …
Excessive workload, overly rigid reporting and organisational indifference are barriers to delivery of compassionate care. IMPLICATIO …
Cochlear pathology, sensory cell death and regeneration.
Raphael Y. Raphael Y. Br Med Bull. 2002;63:25-38. doi: 10.1093/bmb/63.1.25. Br Med Bull. 2002. PMID: 12324382 Review.
Cochlear supporting cells actively participate in the process of hair cell elimination and scar formation by rapidly expanding and sealing the reticular lamina, the barrier between endolymph and perilymph. This scarring process helps preserve the remaining hair cells and h …
Cochlear supporting cells actively participate in the process of hair cell elimination and scar formation by rapidly expanding and sealing t …
Formulation design for topical drug and nanoparticle treatment of skin disease.
Raphael AP, Garrastazu G, Sonvico F, Prow TW. Raphael AP, et al. Ther Deliv. 2015 Feb;6(2):197-216. doi: 10.4155/tde.14.106. Ther Deliv. 2015. PMID: 25690087 Review.
Topical therapeutic and cosmeceutical delivery is a growing field founded on selectively overcoming this barrier. Both the biology of the skin and the nature of the formulation/active ingredient must be aligned for efficient transcutaneous delivery. This review discusses t …
Topical therapeutic and cosmeceutical delivery is a growing field founded on selectively overcoming this barrier. Both the biology of …
Cellular reprogramming with ATOH1, GFI1, and POU4F3 implicate epigenetic changes and cell-cell signaling as obstacles to hair cell regeneration in mature mammals.
Iyer AA, Hosamani I, Nguyen JD, Cai T, Singh S, McGovern MM, Beyer L, Zhang H, Jen HI, Yousaf R, Birol O, Sun JJ, Ray RS, Raphael Y, Segil N, Groves AK. Iyer AA, et al. Elife. 2022 Nov 29;11:e79712. doi: 10.7554/eLife.79712. Elife. 2022. PMID: 36445327 Free PMC article.
Second, signaling from hair cells to supporting cells, including Notch signaling, can prevent reprogramming of many supporting cells to hair cells, even with three hair cell transcription factors. Our results shed light on the molecular barriers that must be overcome to pr …
Second, signaling from hair cells to supporting cells, including Notch signaling, can prevent reprogramming of many supporting cells to hair …
Translating Research into Child Health Policy: Aligning Incentives and Building a New Discourse.
Pulcini CD, Raphael JL, Lopez KN. Pulcini CD, et al. Pediatr Clin North Am. 2023 Feb;70(1):151-164. doi: 10.1016/j.pcl.2022.09.012. Pediatr Clin North Am. 2023. PMID: 36402465 Review.
However, the translation of research into child health policy has often been slow due to misalignments in incentives between researchers and policy makers and a paucity of conceptual models to inform translation. This article outlines barriers to translation, provides exam …
However, the translation of research into child health policy has often been slow due to misalignments in incentives between researchers and …
120 results