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Page 1
Synthesis and Antimycobacterial Evaluation of N-(4-(Benzyloxy)benzyl)-4-aminoquinolines.
Grams ES, Silva Ramos A, Neves Muniz M, Rambo RS, Alberton Perelló M, Sperotto N, Calle González L, Duarte LS, Galina L, Silva Dadda A, Arraché Gonçalves G, Valim Bizarro C, Basso LA, Machado P. Grams ES, et al. Among authors: rambo rs. Molecules. 2022 Apr 15;27(8):2556. doi: 10.3390/molecules27082556. Molecules. 2022. PMID: 35458755 Free PMC article.
Synthesis and Antimycobacterial Activity of 3-Phenyl-1H-indoles.
Jardim Etchart R, Rambo RS, Lopes Abbadi B, Sperotto N, Ev Neves C, Fries Silva F, Dornelles M, Duarte L, Souza Macchi F, Alberton Perelló M, Vescia Lourega R, Valim Bizarro C, Basso LA, Machado P. Jardim Etchart R, et al. Among authors: rambo rs. Molecules. 2021 Aug 25;26(17):5148. doi: 10.3390/molecules26175148. Molecules. 2021. PMID: 34500579 Free PMC article.
Handling the Hurdles on the Way to Anti-tuberculosis Drug Development.
Dalberto PF, de Souza EV, Abbadi BL, Neves CE, Rambo RS, Ramos AS, Macchi FS, Machado P, Bizarro CV, Basso LA. Dalberto PF, et al. Among authors: rambo rs. Front Chem. 2020 Nov 19;8:586294. doi: 10.3389/fchem.2020.586294. eCollection 2020. Front Chem. 2020. PMID: 33330374 Free PMC article. Review.
Antitubercular Activity of Novel 2-(Quinoline-4-yloxy)acetamides with Improved Drug-Like Properties.
Borsoi AF, Alice LM, Sperotto N, Ramos AS, Abbadi BL, Macchi Hopf FS, Silva Dadda AD, Rambo RS, Madeira Silva RB, Paz JD, Pissinate K, Muniz MN, Neves CE, Galina L, González LC, Perelló MA, de Matos Czeczot A, Leyser M, de Oliveira SD, de Araújo Lock G, de Araújo BV, Costa TD, Bizarro CV, Basso LA, Machado P. Borsoi AF, et al. Among authors: rambo rs. ACS Med Chem Lett. 2022 Jul 21;13(8):1337-1344. doi: 10.1021/acsmedchemlett.2c00254. eCollection 2022 Aug 11. ACS Med Chem Lett. 2022. PMID: 35978694 Free PMC article.
EPSP Synthase-Depleted Cells Are Aromatic Amino Acid Auxotrophs in Mycobacterium smegmatis.
Duque-Villegas MA, Abbadi BL, Romero PR, Matter LB, Galina L, Dalberto PF, Rodrigues-Junior VDS, Ducati RG, Roth CD, Rambo RS, de Souza EV, Perello MA, Morbidoni HR, Machado P, Basso LA, Bizarro CV. Duque-Villegas MA, et al. Microbiol Spectr. 2021 Dec 22;9(3):e0000921. doi: 10.1128/Spectrum.00009-21. Epub 2021 Dec 22. Microbiol Spectr. 2021. PMID: 34937164 Free PMC article.
Novel 4-aminoquinolines: Synthesis, inhibition of the Mycobacterium tuberculosis enoyl-acyl carrier protein reductase, antitubercular activity, SAR, and preclinical evaluation.
Paz JD, Denise de Moura Sperotto N, Ramos AS, Pissinate K, da Silva Rodrigues Junior V, Abbadi BL, Borsoi AF, Rambo RS, Corso Minotto AC, da Silva Dadda A, Galina L, Macchi Hopf FS, Muniz MN, Borges Martinelli LK, Roth CD, Madeira Silva RB, Perelló MA, de Matos Czeczot A, Neves CE, Duarte LS, Leyser M, Dias de Oliveira S, Bizarro CV, Machado P, Basso LA. Paz JD, et al. Eur J Med Chem. 2023 Jan 5;245(Pt 1):114908. doi: 10.1016/j.ejmech.2022.114908. Epub 2022 Nov 18. Eur J Med Chem. 2023. PMID: 36435016
11 results