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A Critical Role for Fas-Mediated Off-Target Tumor Killing in T-cell Immunotherapy.
Upadhyay R, Boiarsky JA, Pantsulaia G, Svensson-Arvelund J, Lin MJ, Wroblewska A, Bhalla S, Scholler N, Bot A, Rossi JM, Sadek N, Parekh S, Lagana A, Baccarini A, Merad M, Brown BD, Brody JD. Upadhyay R, et al. Cancer Discov. 2021 Mar;11(3):599-613. doi: 10.1158/2159-8290.CD-20-0756. Epub 2020 Dec 17. Cancer Discov. 2021. PMID: 33334730 Free PMC article.
Expanding cross-presenting dendritic cells enhances oncolytic virotherapy and is critical for long-term anti-tumor immunity.
Svensson-Arvelund J, Cuadrado-Castano S, Pantsulaia G, Kim K, Aleynick M, Hammerich L, Upadhyay R, Yellin M, Marsh H, Oreper D, Jhunjhunwala S, Moussion C, Merad M, Brown BD, García-Sastre A, Brody JD. Svensson-Arvelund J, et al. Among authors: upadhyay r. Nat Commun. 2022 Nov 22;13(1):7149. doi: 10.1038/s41467-022-34791-8. Nat Commun. 2022. PMID: 36418317 Free PMC article.
Lymphoma: immune evasion strategies.
Upadhyay R, Hammerich L, Peng P, Brown B, Merad M, Brody JD. Upadhyay R, et al. Cancers (Basel). 2015 Apr 30;7(2):736-62. doi: 10.3390/cancers7020736. Cancers (Basel). 2015. PMID: 25941795 Free PMC article. Review.
Systemic clinical tumor regressions and potentiation of PD1 blockade with in situ vaccination.
Hammerich L, Marron TU, Upadhyay R, Svensson-Arvelund J, Dhainaut M, Hussein S, Zhan Y, Ostrowski D, Yellin M, Marsh H, Salazar AM, Rahman AH, Brown BD, Merad M, Brody JD. Hammerich L, et al. Among authors: upadhyay r. Nat Med. 2019 May;25(5):814-824. doi: 10.1038/s41591-019-0410-x. Epub 2019 Apr 8. Nat Med. 2019. PMID: 30962585 Clinical Trial.