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Polθ is phosphorylated by PLK1 to repair double-strand breaks in mitosis.
Gelot C, Kovacs MT, Miron S, Mylne E, Haan A, Boeffard-Dosierre L, Ghouil R, Popova T, Dingli F, Loew D, Guirouilh-Barbat J, Del Nery E, Zinn-Justin S, Ceccaldi R. Gelot C, et al. Among authors: ghouil r. Nature. 2023 Sep;621(7978):415-422. doi: 10.1038/s41586-023-06506-6. Epub 2023 Sep 6. Nature. 2023. PMID: 37674080 Free PMC article.
BRCA2-HSF2BP oligomeric ring disassembly by BRME1 promotes homologous recombination.
Ghouil R, Miron S, Sato K, Ristic D, van Rossum-Fikkert SE, Legrand P, Ouldali M, Winter JM, Ropars V, David G, Arteni AA, Wyman C, Knipscheer P, Kanaar R, Zelensky AN, Zinn-Justin S. Ghouil R, et al. Sci Adv. 2023 Oct 27;9(43):eadi7352. doi: 10.1126/sciadv.adi7352. Epub 2023 Oct 27. Sci Adv. 2023. PMID: 37889963 Free PMC article.
Multiple Site-Specific Phosphorylation of IDPs Monitored by NMR.
Julien M, Bouguechtouli C, Alik A, Ghouil R, Zinn-Justin S, Theillet FX. Julien M, et al. Among authors: ghouil r. Methods Mol Biol. 2020;2141:793-817. doi: 10.1007/978-1-0716-0524-0_41. Methods Mol Biol. 2020. PMID: 32696390 Free article.
BRCA2 binding through a cryptic repeated motif to HSF2BP oligomers does not impact meiotic recombination.
Ghouil R, Miron S, Koornneef L, Veerman J, Paul MW, Le Du MH, Sleddens-Linkels E, van Rossum-Fikkert SE, van Loon Y, Felipe-Medina N, Pendas AM, Maas A, Essers J, Legrand P, Baarends WM, Kanaar R, Zinn-Justin S, Zelensky AN. Ghouil R, et al. Nat Commun. 2021 Jul 29;12(1):4605. doi: 10.1038/s41467-021-24871-6. Nat Commun. 2021. PMID: 34326328 Free PMC article.