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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1869 1
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1933 1
1945 9
1946 2
1947 6
1948 2
1949 3
1950 15
1951 7
1952 13
1953 9
1954 6
1955 19
1956 21
1957 17
1958 30
1959 9
1963 15
1964 20
1965 25
1966 33
1967 25
1968 44
1969 43
1970 34
1971 42
1972 44
1973 31
1974 51
1975 86
1976 97
1977 91
1978 95
1979 124
1980 116
1981 118
1982 117
1983 149
1984 179
1985 177
1986 146
1987 192
1988 192
1989 230
1990 224
1991 256
1992 262
1993 213
1994 232
1995 266
1996 265
1997 307
1998 352
1999 341
2000 354
2001 372
2002 369
2003 395
2004 423
2005 450
2006 479
2007 555
2008 588
2009 671
2010 683
2011 736
2012 826
2013 1029
2014 1140
2015 1226
2016 1276
2017 1372
2018 1548
2019 1630
2020 2172
2021 2329
2022 2542
2023 2659
2024 1089

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29,298 results

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The following term was not found in PubMed: Lu-Andrews
Page 1
Ran GTPase and Its Importance in Cellular Signaling and Malignant Phenotype.
El-Tanani M, Nsairat H, Mishra V, Mishra Y, Aljabali AAA, Serrano-Aroca Á, Tambuwala MM. El-Tanani M, et al. Int J Mol Sci. 2023 Feb 4;24(4):3065. doi: 10.3390/ijms24043065. Int J Mol Sci. 2023. PMID: 36834476 Free PMC article. Review.
In vitro, Ran overexpression has severe effects on the cell phenotype, altering proliferation, adhesion, colony density, and invasion. ...The increased malignancy and invasiveness have been attributed to multiple mechanisms. Increased dependence on Ran for spindle f …
In vitro, Ran overexpression has severe effects on the cell phenotype, altering proliferation, adhesion, colony density, and invasion …
Repeat-associated non-AUG (RAN) translation: insights from pathology.
Banez-Coronel M, Ranum LPW. Banez-Coronel M, et al. Lab Invest. 2019 Jul;99(7):929-942. doi: 10.1038/s41374-019-0241-x. Epub 2019 Mar 27. Lab Invest. 2019. PMID: 30918326 Free PMC article. Review.
More than 40 different neurological diseases are caused by microsatellite repeat expansions. Since the discovery of repeat-associated non-AUG (RAN) translation by Zu et al. in 2011, nine expansion disorders have been identified as RAN-positive diseases. ...In some d …
More than 40 different neurological diseases are caused by microsatellite repeat expansions. Since the discovery of repeat-associated non-AU …
Complementary functions for the Ran gradient during division.
Ozugergin I, Piekny A. Ozugergin I, et al. Small GTPases. 2021 May;12(3):177-187. doi: 10.1080/21541248.2020.1725371. Epub 2020 Feb 14. Small GTPases. 2021. PMID: 32013678 Free PMC article. Review.
The Ran pathway has a well-described function in nucleocytoplasmic transport, where active Ran dissociates importin/karyopherin-bound cargo containing a nuclear localization signal (NLS) in the nucleus. As cells enter mitosis, the nuclear envelope breaks down and a …
The Ran pathway has a well-described function in nucleocytoplasmic transport, where active Ran dissociates importin/karyopheri …
Measuring Repeat-Associated Non-AUG (RAN) Translation.
Wang S, Sun S. Wang S, et al. Methods Mol Biol. 2022;2428:113-132. doi: 10.1007/978-1-0716-1975-9_8. Methods Mol Biol. 2022. PMID: 35171477
Many repeat expansion-containing RNAs can generate toxic repeat proteins through repeat-associated non-AUG (RAN) translation in all the reading frames. Understanding how RAN translation occurs and what cellular factors regulate this process will help decipher the ba …
Many repeat expansion-containing RNAs can generate toxic repeat proteins through repeat-associated non-AUG (RAN) translation in all t …
Ran GTPase: A Key Player in Tumor Progression and Metastasis.
Boudhraa Z, Carmona E, Provencher D, Mes-Masson AM. Boudhraa Z, et al. Front Cell Dev Biol. 2020 May 26;8:345. doi: 10.3389/fcell.2020.00345. eCollection 2020. Front Cell Dev Biol. 2020. PMID: 32528950 Free PMC article. Review.
Ran (Ras-related nuclear protein) GTPase is a member of the Ras superfamily. Like all the GTPases, Ran cycles between an active (GTP-bound) and inactive (GDP-bound) state. ...
Ran (Ras-related nuclear protein) GTPase is a member of the Ras superfamily. Like all the GTPases, Ran cycles between an activ …
Evolution and function of bacterial RCC1 repeat effectors.
Swart AL, Gomez-Valero L, Buchrieser C, Hilbi H. Swart AL, et al. Cell Microbiol. 2020 Oct;22(10):e13246. doi: 10.1111/cmi.13246. Epub 2020 Aug 26. Cell Microbiol. 2020. PMID: 32720355 Free article. Review.
The RCC1 repeat effectors localise to the pathogen vacuole or the host plasma membrane and target distinct components of the Ran GTPase cycle, including Ran modulators and the small GTPase itself. ...Hence, divergent evolution of bacterial RCC1 repeat effectors defi …
The RCC1 repeat effectors localise to the pathogen vacuole or the host plasma membrane and target distinct components of the Ran GTPa …
Repeat-associated non-AUG translation induces cytoplasmic aggregation of CAG repeat-containing RNAs.
Das MR, Chang Y, Anderson R, Saunders RA, Zhang N, Tomberlin CP, Vale RD, Jain A. Das MR, et al. Proc Natl Acad Sci U S A. 2023 Jan 17;120(3):e2215071120. doi: 10.1073/pnas.2215071120. Epub 2023 Jan 9. Proc Natl Acad Sci U S A. 2023. PMID: 36623192 Free PMC article.
The relationship between RAN translation and RNA foci, and their relative contributions to cellular dysfunction, are unclear. ...In the cytoplasm, these RNAs are initially dispersed but, upon RAN translation, aggregate with the RAN translation products. These …
The relationship between RAN translation and RNA foci, and their relative contributions to cellular dysfunction, are unclear. ...In t …
Repeat-associated non-ATG (RAN) translation.
Cleary JD, Pattamatta A, Ranum LPW. Cleary JD, et al. J Biol Chem. 2018 Oct 19;293(42):16127-16141. doi: 10.1074/jbc.R118.003237. Epub 2018 Sep 13. J Biol Chem. 2018. PMID: 30213863 Free PMC article.
These repeat expansion mutations can produce repeat-associated non-ATG (RAN) proteins in all three reading frames, which accumulate in disease-relevant tissues. ...Understanding how RAN translation occurs, what cellular factors contribute to RAN protein accum …
These repeat expansion mutations can produce repeat-associated non-ATG (RAN) proteins in all three reading frames, which accumulate i …
Two-way trafficking with Ran.
Melchior F, Gerace L. Melchior F, et al. Trends Cell Biol. 1998 May;8(5):175-9. doi: 10.1016/s0962-8924(98)01252-5. Trends Cell Biol. 1998. PMID: 9695834 Review.
The small Ras-related GTPase Ran is directly involved in nuclear protein import and export. However, the question of how Ran functions in transport is highly controversial. ...Comparison of Ran with the translation elongation factor Ef-Tu raises the possibili …
The small Ras-related GTPase Ran is directly involved in nuclear protein import and export. However, the question of how Ran f …
The Ran-GTPase and cell-cycle control.
Moore JD. Moore JD. Bioessays. 2001 Jan;23(1):77-85. doi: 10.1002/1521-1878(200101)23:1<77::AID-BIES1010>3.0.CO;2-E. Bioessays. 2001. PMID: 11135312 Review.
RCC1, the chromatin-bound guanine-nucleotide exchange factor (GEF) for the small nuclear GTPase, Ran, is required for coordinating the onset of mitosis with S-phase completion in mammalian cells. ...However, the Ran system is now best known for its pivotal role in n …
RCC1, the chromatin-bound guanine-nucleotide exchange factor (GEF) for the small nuclear GTPase, Ran, is required for coordinating th …
29,298 results
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