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Customizably designed multibodies neutralize SARS-CoV-2 in a variant-insensitive manner.
Abreu C, Ortega C, Olivero-Deibe N, Carrión F, Gaete-Argel A, Valiente-Echeverría F, Soto-Rifo R, Milan Bonotto R, Marcello A, Pantano S. Abreu C, et al. Among authors: milan bonotto r. Front Immunol. 2023 Aug 10;14:1226880. doi: 10.3389/fimmu.2023.1226880. eCollection 2023. Front Immunol. 2023. PMID: 37638023 Free PMC article.
The cholesterol metabolite 27-hydroxycholesterol inhibits SARS-CoV-2 and is markedly decreased in COVID-19 patients.
Marcello A, Civra A, Milan Bonotto R, Nascimento Alves L, Rajasekharan S, Giacobone C, Caccia C, Cavalli R, Adami M, Brambilla P, Lembo D, Poli G, Leoni V. Marcello A, et al. Among authors: milan bonotto r. Redox Biol. 2020 Sep;36:101682. doi: 10.1016/j.redox.2020.101682. Epub 2020 Aug 10. Redox Biol. 2020. PMID: 32810737 Free PMC article.
Characterisation of the Antibody Response in Sinopharm (BBIBP-CorV) Recipients and COVID-19 Convalescent Sera from the Republic of Moldova.
Ulinici M, Suljič A, Poggianella M, Milan Bonotto R, Resman Rus K, Paraschiv A, Bonetti AM, Todiras M, Corlateanu A, Groppa S, Ceban E, Petrovec M, Marcello A. Ulinici M, et al. Among authors: milan bonotto r. Vaccines (Basel). 2023 Mar 13;11(3):637. doi: 10.3390/vaccines11030637. Vaccines (Basel). 2023. PMID: 36992221 Free PMC article.
Biological Properties of a Novel Multifunctional Host Defense Peptide from the Skin Secretion of the Chaco Tree Frog, Boana raniceps.
Santana CJC, Magalhães ACM, Prías-Márquez CA, Falico DA, Dos Santos Júnior ACM, Lima BD, Ricart CAO, de Pilger DRB, Bonotto RM, Moraes CB, Freitas-Júnior LH, Álvares ADCM, Freitas SM, Luz IS, Pires OR Jr, Fontes W, Castro MS. Santana CJC, et al. Among authors: bonotto rm. Biomolecules. 2020 May 20;10(5):790. doi: 10.3390/biom10050790. Biomolecules. 2020. PMID: 32443921 Free PMC article.
High content screening of a kinase-focused library reveals compounds broadly-active against dengue viruses.
Cruz DJ, Koishi AC, Taniguchi JB, Li X, Milan Bonotto R, No JH, Kim KH, Baek S, Kim HY, Windisch MP, Pamplona Mosimann AL, de Borba L, Liuzzi M, Hansen MA, Duarte dos Santos CN, Freitas-Junior LH. Cruz DJ, et al. Among authors: milan bonotto r. PLoS Negl Trop Dis. 2013;7(2):e2073. doi: 10.1371/journal.pntd.0002073. Epub 2013 Feb 21. PLoS Negl Trop Dis. 2013. PMID: 23437413 Free PMC article.