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Page 1
Synthesis of new 18F-radiolabeled silicon-based nitroimidazole compounds.
Bioorg Med Chem. 2013 Jul 1;21(13):3680-8. doi: 10.1016/j.bmc.2013.04.029. Epub 2013 Apr 22.
Bioorg Med Chem. 2013.
PMID: 23665140
Donepezil-Based Central Acetylcholinesterase Inhibitors by Means of a "Bio-Oxidizable" Prodrug Strategy: Design, Synthesis, and in Vitro Biological Evaluation.
Peauger L, Azzouz R, Gembus V, Ţînţaş ML, Sopková-de Oliveira Santos J, Bohn P, Papamicaël C, Levacher V.
Peauger L, et al. Among authors: azzouz r.
J Med Chem. 2017 Jul 13;60(13):5909-5926. doi: 10.1021/acs.jmedchem.7b00702. Epub 2017 Jun 29.
J Med Chem. 2017.
PMID: 28613859
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Design, Synthesis, and In Vitro Biological Activities of a Bio-Oxidizable Prodrug to Deliver Both ChEs and DYRK1A Inhibitors for AD Therapy.
Barré A, Azzouz R, Gembus V, Papamicaël C, Levacher V.
Barré A, et al. Among authors: azzouz r.
Molecules. 2019 Apr 1;24(7):1264. doi: 10.3390/molecules24071264.
Molecules. 2019.
PMID: 30939771
Free PMC article.
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Access to Highly Enantioenriched Donepezil-like 1,4-Dihydropyridines as Promising Anti-Alzheimer Prodrug Candidates via Enantioselective Tsuji Allylation and Organocatalytic Aza-Ene-Type Domino Reactions.
Ţînţaş ML, Azzouz R, Peauger L, Gembus V, Petit E, Bailly L, Papamicaël C, Levacher V.
Ţînţaş ML, et al. Among authors: azzouz r.
J Org Chem. 2018 Sep 7;83(17):10231-10240. doi: 10.1021/acs.joc.8b01442. Epub 2018 Jul 24.
J Org Chem. 2018.
PMID: 30004228
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Novel donepezil-like N-benzylpyridinium salt derivatives as AChE inhibitors and their corresponding dihydropyridine "bio-oxidizable" prodrugs: Synthesis, biological evaluation and structure-activity relationship.
Azzouz R, Peauger L, Gembus V, Ţînţaş ML, Sopková-de Oliveira Santos J, Papamicaël C, Levacher V.
Azzouz R, et al.
Eur J Med Chem. 2018 Feb 10;145:165-190. doi: 10.1016/j.ejmech.2017.12.084. Epub 2017 Dec 27.
Eur J Med Chem. 2018.
PMID: 29324339
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A concise synthesis of lentiginosine derivatives using a pyridinium formation via the Mitsunobu reaction.
Azzouz R, Fruit C, Bischoff L, Marsais F.
Azzouz R, et al.
J Org Chem. 2008 Feb 1;73(3):1154-7. doi: 10.1021/jo702141b. Epub 2008 Jan 8.
J Org Chem. 2008.
PMID: 18179231
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Design of silicon-based misonidazole analogues and (18)F-radiolabelling.
Bohn P, Deyine A, Azzouz R, Bailly L, Fiol-Petit C, Bischoff L, Fruit C, Marsais F, Vera P.
Bohn P, et al. Among authors: azzouz r.
Nucl Med Biol. 2009 Nov;36(8):895-905. doi: 10.1016/j.nucmedbio.2009.06.004. Epub 2009 Oct 3.
Nucl Med Biol. 2009.
PMID: 19875046
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