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Did you mean R.S. moxham (1 results)?
Epimers of moxalactam: in vitro comparison of activity and stability.
Wise R, Wills PJ, Bedford KA. Wise R, et al. Antimicrob Agents Chemother. 1981 Jul;20(1):30-2. doi: 10.1128/AAC.20.1.30. Antimicrob Agents Chemother. 1981. PMID: 6456687 Free PMC article.
Moxalactam exists in two epimeric forms, R and S. The in vitro activity of these two epimers was compared with that of material available for clinical and laboratory use (R + S moxalactam). Generally, R moxalactam was twice as active as the S fo …
Moxalactam exists in two epimeric forms, R and S. The in vitro activity of these two epimers was compared with that of material avail …
Activity, stability, and pharmacology of the epimers of moxalactam.
Wise R, Wright N, Wills PJ. Wise R, et al. Rev Infect Dis. 1982 Nov-Dec;4 Suppl:S564-8. doi: 10.1093/clinids/4.supplement_3.s564. Rev Infect Dis. 1982. PMID: 6218567
By an agar-dilution procedure, the minimal inhibitory concentrations of R, S, and R + S epimers of moxalactam were determined for 23 commonly isolated organisms. ...In serum, however, the R:S ratio of the mixture at equilibrium was …
By an agar-dilution procedure, the minimal inhibitory concentrations of R, S, and R + S epimers of moxalactam …
Maternal and fetal pharmacokinetics of moxalactam given intrapartum.
Bawdon RE, Cunningham FG, Quirk JG, Roark ML. Bawdon RE, et al. Am J Obstet Gynecol. 1982 Nov 1;144(5):546-50. doi: 10.1016/0002-9378(82)90225-3. Am J Obstet Gynecol. 1982. PMID: 6215864
Two grams of moxalactam was given intravenously to 28 women at high risk for infection following cesarean delivery. ...R and S epimeric distribution was determined in these sera and tissues, and the mean R/S ratios were 0.95, 0.93, and 1.22 for the three grou …
Two grams of moxalactam was given intravenously to 28 women at high risk for infection following cesarean delivery. ...R and S epimer …
Moxalactam epimer kinetics in children.
Nahata MC, Durrell DE, Barson WJ. Nahata MC, et al. Clin Pharmacol Ther. 1982 Apr;31(4):528-32. doi: 10.1038/clpt.1982.71. Clin Pharmacol Ther. 1982. PMID: 6460588
Total body clearance and apparent volume of distribution of the R epimer were higher than those of the S epimer (P less than 0.004). Total body clearance of R, S, and R + S moxalactam ranged from 29.01 to 183.7, 19.00 to 79.95, and 23.34 to 113. …
Total body clearance and apparent volume of distribution of the R epimer were higher than those of the S epimer (P less than 0.004). Total b …
Investigation of human bile and serum levels by high pressure liquid chromatography after administration of latamoxef or cefotaxime.
Krausse R, Ullmann U, Brandstetter G, Kratochvil P. Krausse R, et al. Arzneimittelforschung. 1984;34(12):1787-91. Arzneimittelforschung. 1984. PMID: 6099130
Desacetylcefotaxime concentration in bile after 1 and 2 h was four to five times higher than in serum. The ratio R-:S-epimer of latamoxef in serum was 49:51 after 1 and 2 h, in bile 44:56 after 1 h and 48:52 after 2 h. ...
Desacetylcefotaxime concentration in bile after 1 and 2 h was four to five times higher than in serum. The ratio R-:S-epimer o …
Epimerization kinetics of moxalactam in frozen urine and plasma samples.
Hashimoto N, Ichihashi T, Hirano K, Yamada H. Hashimoto N, et al. Pharm Res. 1990 Apr;7(4):364-9. doi: 10.1023/a:1015815321570. Pharm Res. 1990. PMID: 2362909
The R/S ratio at equilibrium [(R/S)eq] at -10 degrees C was similar in urine and in rat and human plasma ultrafiltrate but differed from that in water. ...Consequently, the biological LMOX samples should be preserved at or below -70 degrees C to preven …
The R/S ratio at equilibrium [(R/S)eq] at -10 degrees C was similar in urine and in rat and human plasma ultrafi …