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Meta-Analysis of 26 638 Individuals Identifies Two Genetic Loci Associated With Left Ventricular Ejection Fraction.
Circ Genom Precis Med. 2020 Aug;13(4):e002804. doi: 10.1161/CIRCGEN.119.002804. Epub 2020 Jun 30.
Circ Genom Precis Med. 2020.
PMID: 32605384
Free PMC article.
RESULTS: A meta-analysis combining results from Genetic Epidemiology Research on Adult Health and Aging and UK Biobank identified a novel locus: TMEM40 on chromosome 3p25 (rs11719526; beta=0.47 and P=3.1010(-8)) that replicated in Biobank Japan and confirmed recent finding …
RESULTS: A meta-analysis combining results from Genetic Epidemiology Research on Adult Health and Aging and UK Biobank identified a novel lo …
Characterization of Statin Low-Density Lipoprotein Cholesterol Dose-Response Using Electronic Health Records in a Large Population-Based Cohort.
Oni-Orisan A, Hoffmann TJ, Ranatunga D, Medina MW, Jorgenson E, Schaefer C, Krauss RM, Iribarren C, Risch N.
Oni-Orisan A, et al.
Circ Genom Precis Med. 2018 Sep;11(9):e002043. doi: 10.1161/CIRCGEN.117.002043.
Circ Genom Precis Med. 2018.
PMID: 30354326
Free PMC article.
RESULTS: Defined daily dose and LDL-C response was associated in a log-linear relationship (beta, -6.17; SE, 0.09; P<10(-300)) which remained significant after adjusting for prespecified covariates (adjusted beta, -5.59; SE, 0.12; P<10(-300)). ...Based on a va …
RESULTS: Defined daily dose and LDL-C response was associated in a log-linear relationship (beta, -6.17; SE, 0.09; P<10(-300)) whi …
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