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Novel genetically encoded fluorescent probes enable real-time detection of potassium in vitro and in vivo.
Bischof H, Rehberg M, Stryeck S, Artinger K, Eroglu E, Waldeck-Weiermair M, Gottschalk B, Rost R, Deak AT, Niedrist T, Vujic N, Lindermuth H, Prassl R, Pelzmann B, Groschner K, Kratky D, Eller K, Rosenkranz AR, Madl T, Plesnila N, Graier WF, Malli R. Bischof H, et al. Nat Commun. 2017 Nov 10;8(1):1422. doi: 10.1038/s41467-017-01615-z. Nat Commun. 2017. PMID: 29127288 Free PMC article.
Renewal of the air-water interface as a critical system parameter of protein stability: aggregation of the human growth hormone and its prevention by surface-active compounds.
Wiesbauer J, Prassl R, Nidetzky B. Wiesbauer J, et al. Langmuir. 2013 Dec 10;29(49):15240-50. doi: 10.1021/la4028223. Epub 2013 Nov 25. Langmuir. 2013. PMID: 24224491
We show that in spite of comparable time-averaged values for a(G/L) ( 100 m(2)/m(3)), aeration gave a 40-fold higher r(agg) than stirring. The enhanced r(agg) under aeration was ascribed to faster macroscopic regeneration of free a(G/L) during aeration as compared t …
We show that in spite of comparable time-averaged values for a(G/L) ( 100 m(2)/m(3)), aeration gave a 40-fold higher r(agg) than stir …
Efficient computation of electrograms and ECGs in human whole heart simulations using a reaction-eikonal model.
Neic A, Campos FO, Prassl AJ, Niederer SA, Bishop MJ, Vigmond EJ, Plank G. Neic A, et al. J Comput Phys. 2017 Oct 1;346:191-211. doi: 10.1016/j.jcp.2017.06.020. J Comput Phys. 2017. PMID: 28819329 Free PMC article.
In this study we report on the development of a novel computationally efficient reaction-eikonal (R-E) model for modeling extracellular potential maps and electrograms. ...Due to their efficiency R-E models are ideally suitable for forward simulations in clinical mo …
In this study we report on the development of a novel computationally efficient reaction-eikonal (R-E) model for modeling extracellul …
Diminished quality of life in patients with cancer correlates with tryptophan degradation.
Schroecksnadel K, Fiegl M, Prassl K, Winkler C, Denz HA, Fuchs D. Schroecksnadel K, et al. J Cancer Res Clin Oncol. 2007 Jul;133(7):477-85. doi: 10.1007/s00432-007-0191-3. Epub 2007 Mar 14. J Cancer Res Clin Oncol. 2007. PMID: 17356858
Serum tryptophan concentrations were lower in patients with progressive disease (P < 0.01), and decreased tryptophan concentrations were related to decreased QoL (r(s) = 0.256, P < 0.01) and increased fatigue (r(s) = -0.179; P < 0.05). ...

Serum tryptophan concentrations were lower in patients with progressive disease (P < 0.01), and decreased tryptophan concentrations were