[Molecular epidemiology of carbapenem-resistant isolates of Acinetobacter baumannii in Argentina]

Rev Argent Microbiol. 2019 Jul-Sep;51(3):247-250. doi: 10.1016/j.ram.2017.12.004. Epub 2018 Dec 12.
[Article in Spanish]

Abstract

One hundred sequential, epidemiologically unrelated carbapenem-resistant- Acinetobacter baumannii isolates from 11 hospitals in 10 Argentine provinces were collected between January and August 2016. Genes coding for Ambler class D and B carbapenemases were investigated by PCR using specific primers. All isolates were typed using the 3-locus sequence typing and blaOXA-51-like sequence-based typing techniques. The blaOXA-23 gene was recovered in all isolates studied. The population of carbapenem-resistant- A. baumannii in Argentina was principally associated with ST1 (45%), ST25 (34%) and ST79 (15%). ST25 was recovered in all the regions studied and CC2 was not detected.

Keywords: Acinetobacter baumannii; CC1; CC25; Carbapenem-resistance; Resistencia a carbapenems.

Publication types

  • Comparative Study

MeSH terms

  • Acinetobacter Infections / epidemiology
  • Acinetobacter Infections / microbiology*
  • Acinetobacter baumannii / drug effects
  • Acinetobacter baumannii / enzymology
  • Acinetobacter baumannii / genetics
  • Acinetobacter baumannii / isolation & purification*
  • Argentina / epidemiology
  • Bacterial Proteins / genetics*
  • Carbapenems / pharmacology*
  • Cross Infection / epidemiology
  • Cross Infection / microbiology*
  • Humans
  • beta-Lactam Resistance*
  • beta-Lactamases / genetics*

Substances

  • Bacterial Proteins
  • Carbapenems
  • beta-Lactamases
  • beta-lactamase OXA-23, Acinetobacter baumannii