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Showing results for R. K. nisbet
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Dupilumab for COPD with Type 2 Inflammation Indicated by Eosinophil Counts.
Bhatt SP, Rabe KF, Hanania NA, Vogelmeier CF, Cole J, Bafadhel M, Christenson SA, Papi A, Singh D, Laws E, Mannent LP, Patel N, Staudinger HW, Yancopoulos GD, Mortensen ER, Akinlade B, Maloney J, Lu X, Bauer D, Bansal A, Robinson LB, Abdulai RM; BOREAS Investigators. Bhatt SP, et al. N Engl J Med. 2023 Jul 20;389(3):205-214. doi: 10.1056/NEJMoa2303951. Epub 2023 May 21. N Engl J Med. 2023. PMID: 37272521 Clinical Trial.
Triple Inhaled Therapy at Two Glucocorticoid Doses in Moderate-to-Very-Severe COPD.
Rabe KF, Martinez FJ, Ferguson GT, Wang C, Singh D, Wedzicha JA, Trivedi R, St Rose E, Ballal S, McLaren J, Darken P, Aurivillius M, Reisner C, Dorinsky P; ETHOS Investigators. Rabe KF, et al. N Engl J Med. 2020 Jul 2;383(1):35-48. doi: 10.1056/NEJMoa1916046. Epub 2020 Jun 24. N Engl J Med. 2020. PMID: 32579807 Clinical Trial.
Benralizumab for the Prevention of COPD Exacerbations.
Criner GJ, Celli BR, Brightling CE, Agusti A, Papi A, Singh D, Sin DD, Vogelmeier CF, Sciurba FC, Bafadhel M, Backer V, Kato M, Ramírez-Venegas A, Wei YF, Bjermer L, Shih VH, Jison M, O'Quinn S, Makulova N, Newbold P, Goldman M, Martin UJ; GALATHEA Study Investigators; TERRANOVA Study Investigators. Criner GJ, et al. N Engl J Med. 2019 Sep 12;381(11):1023-1034. doi: 10.1056/NEJMoa1905248. Epub 2019 May 20. N Engl J Med. 2019. PMID: 31112385 Clinical Trial.
Tissue Equivalent Curved Organic X-ray Detectors Utilizing High Atomic Number Polythiophene Analogues.
Nanayakkara MPA, He Q, Ruseckas A, Karalasingam A, Matjacic L, Masteghin MG, Basiricò L, Fratelli I, Ciavatti A, Kilbride RC, Jenatsch S, Parnell AJ, Fraboni B, Nisbet A, Heeney M, Jayawardena KDGI, Silva SRP. Nanayakkara MPA, et al. Adv Sci (Weinh). 2023 Dec;10(35):e2304261. doi: 10.1002/advs.202304261. Epub 2023 Nov 2. Adv Sci (Weinh). 2023. PMID: 37916896 Free PMC article.
An improved, optimised and robust keratin azure assay for accurate assessment of keratinase activity.
Cowan RM, Birch E, Nisbet G, Onyeiwu C, Campbell C, Archer I, Campopiano DJ. Cowan RM, et al. Anal Methods. 2023 Nov 30;15(46):6468-6475. doi: 10.1039/d3ay01433a. Anal Methods. 2023. PMID: 37982303
A colourimetric method monitored the keratinase activity of Proteinase K (PK), which degrades the KA substrate and releases soluble products that are observed at 595 nm. Initially, the azure dye standard, Remazol Brilliant Blue R (RBBR), was used to calibrate the as …
A colourimetric method monitored the keratinase activity of Proteinase K (PK), which degrades the KA substrate and releases soluble p …
Localized bioelectrical conduction block from radiofrequency gastric ablation persists after healing: safety and feasibility in a recovery model.
Aghababaie Z, O'Grady G, Nisbet LA, Modesto AE, Chan CA, Matthee A, Amirapu S, Beyder A, Farrugia G, Asirvatham SJ, Sands GB, Paskaranandavadivel N, Cheng LK, Angeli-Gordon TR. Aghababaie Z, et al. Am J Physiol Gastrointest Liver Physiol. 2022 Dec 1;323(6):G640-G652. doi: 10.1152/ajpgi.00116.2022. Epub 2022 Oct 18. Am J Physiol Gastrointest Liver Physiol. 2022. PMID: 36255716 Free PMC article.
Randomized Trial of Endoscopic or Open Vein-Graft Harvesting for Coronary-Artery Bypass.
Zenati MA, Bhatt DL, Bakaeen FG, Stock EM, Biswas K, Gaziano JM, Kelly RF, Tseng EE, Bitondo J, Quin JA, Almassi GH, Haime M, Hattler B, DeMatt E, Scrymgeour A, Huang GD; REGROUP Trial Investigators. Zenati MA, et al. N Engl J Med. 2019 Jan 10;380(2):132-141. doi: 10.1056/NEJMoa1812390. Epub 2018 Nov 11. N Engl J Med. 2019. PMID: 30417737 Clinical Trial.
Cosmetic benefit of a biomimetic lamellar cream formulation on barrier function or the appearance of fine lines and wrinkles in randomized proof-of-concept clinical studies.
Nisbet S, Mahalingam H, Gfeller CF, Biggs E, Lucas S, Thompson M, Cargill MR, Moore D, Bielfeldt S. Nisbet S, et al. Int J Cosmet Sci. 2019 Feb;41(1):1-11. doi: 10.1111/ics.12499. Epub 2019 Feb 22. Int J Cosmet Sci. 2019. PMID: 30414275 Free PMC article. Clinical Trial.
In Study 2 (n = 72 subjects with visible signs of ageing), there was a favourable trend in the change from baseline of a skin roughness parameter, R(a) , for the test cream compared to no treatment. There were statistically significant improvements in the Fitzpatrick wrink …
In Study 2 (n = 72 subjects with visible signs of ageing), there was a favourable trend in the change from baseline of a skin roughness para …
Expression of phosphofructokinase in skeletal muscle is influenced by genetic variation and associated with insulin sensitivity.
Keildson S, Fadista J, Ladenvall C, Hedman ÅK, Elgzyri T, Small KS, Grundberg E, Nica AC, Glass D, Richards JB, Barrett A, Nisbet J, Zheng HF, Rönn T, Ström K, Eriksson KF, Prokopenko I; MAGIC Consortium; DIAGRAM Consortium; MuTHER Consortium; Spector TD, Dermitzakis ET, Deloukas P, McCarthy MI, Rung J, Groop L, Franks PW, Lindgren CM, Hansson O. Keildson S, et al. Diabetes. 2014 Mar;63(3):1154-65. doi: 10.2337/db13-1301. Epub 2013 Dec 4. Diabetes. 2014. PMID: 24306210 Free PMC article.
We explored eQTL results using published data from genome-wide association studies (DIAGRAM and MAGIC), and a proxy for the PFKM eQTL (rs11168327; r(2) = 0.75) was nominally associated with T2D (DIAGRAM P = 2.7 10(-3)). ...
We explored eQTL results using published data from genome-wide association studies (DIAGRAM and MAGIC), and a proxy for the PFKM eQTL (rs111 …
The 5-HT1 receptor agonist RU-24969 decreases 5-hydroxytryptamine (5-HT) release and metabolism in the rat frontal cortex in vitro and in vivo.
Brazell MP, Marsden CA, Nisbet AP, Routledge C. Brazell MP, et al. Br J Pharmacol. 1985 Sep;86(1):209-16. doi: 10.1111/j.1476-5381.1985.tb09451.x. Br J Pharmacol. 1985. PMID: 2413936 Free PMC article.
K+-stimulated release of [3H]-5-hydroxytryptamine ( [3H]-5-HT) from rat frontal cortex slices was decreased by the 5-HT receptor agonists 5-methoxy-n1N-dimethyltryptamine and 5-methoxy-3(1,2,3,6,-tetrahydro-4-pyrindinyl)-1H-indole (RU-24969) (1 X 10(-5)M). ...The non-selec …
K+-stimulated release of [3H]-5-hydroxytryptamine ( [3H]-5-HT) from rat frontal cortex slices was decreased by the 5-HT receptor agon …