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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2003 1
2004 1
2006 1
2007 1
2008 2
2009 2
2010 3
2011 1
2012 3
2013 1
2014 2
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2017 2
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2019 2
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2022 9
2023 2
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Page 1
LRRK2 Phosphorylation.
Nichols RJ. Nichols RJ. Adv Neurobiol. 2017;14:51-70. doi: 10.1007/978-3-319-49969-7_3. Adv Neurobiol. 2017. PMID: 28353278 Review.
Targeting LRRK2 mutations in Parkinson's disease.
Leśniak RK, Nichols RJ, Smith M, Montine TJ. Leśniak RK, et al. Future Med Chem. 2022 Aug;14(16):1167-1170. doi: 10.4155/fmc-2022-0102. Epub 2022 Jun 22. Future Med Chem. 2022. PMID: 35730403 Free article. No abstract available.
Editorial: LRRK2-Fifteen Years From Cloning to the Clinic.
Rideout H, Greggio E, Kortholt A, Nichols RJ. Rideout H, et al. Among authors: nichols rj. Front Neurosci. 2022 Apr 11;16:880914. doi: 10.3389/fnins.2022.880914. eCollection 2022. Front Neurosci. 2022. PMID: 35478845 Free PMC article. No abstract available.
The E3 ligase TRIM1 ubiquitinates LRRK2 and controls its localization, degradation, and toxicity.
Stormo AED, Shavarebi F, FitzGibbon M, Earley EM, Ahrendt H, Lum LS, Verschueren E, Swaney DL, Skibinski G, Ravisankar A, van Haren J, Davis EJ, Johnson JR, Von Dollen J, Balen C, Porath J, Crosio C, Mirescu C, Iaccarino C, Dauer WT, Nichols RJ, Wittmann T, Cox TC, Finkbeiner S, Krogan NJ, Oakes SA, Hiniker A. Stormo AED, et al. Among authors: nichols rj. J Cell Biol. 2022 Apr 4;221(4):e202010065. doi: 10.1083/jcb.202010065. Epub 2022 Mar 10. J Cell Biol. 2022. PMID: 35266954 Free PMC article.
PAK6-mediated phosphorylation of PPP2R2C regulates LRRK2-PP2A complex formation.
Iannotta L, Emanuele M, Favetta G, Tombesi G, Vandewynckel L, Lara Ordóñez AJ, Saliou JM, Drouyer M, Sibran W, Civiero L, Nichols RJ, Athanasopoulos PS, Kortholt A, Chartier-Harlin MC, Greggio E, Taymans JM. Iannotta L, et al. Among authors: nichols rj. Front Mol Neurosci. 2023 Dec 18;16:1269387. doi: 10.3389/fnmol.2023.1269387. eCollection 2023. Front Mol Neurosci. 2023. PMID: 38169846 Free PMC article.
LRRK2 dephosphorylation increases its ubiquitination.
Zhao J, Molitor TP, Langston JW, Nichols RJ. Zhao J, et al. Among authors: nichols rj. Biochem J. 2015 Jul 1;469(1):107-20. doi: 10.1042/BJ20141305. Epub 2015 May 5. Biochem J. 2015. PMID: 25939886 Free PMC article.
Discovery of 1H-Pyrazole Biaryl Sulfonamides as Novel G2019S-LRRK2 Kinase Inhibitors.
Leśniak RK, Nichols RJ, Schonemann M, Zhao J, Gajera CR, Lam G, Nguyen KC, Langston JW, Smith M, Montine TJ. Leśniak RK, et al. Among authors: nichols rj. ACS Med Chem Lett. 2022 May 23;13(6):981-988. doi: 10.1021/acsmedchemlett.2c00116. eCollection 2022 Jun 9. ACS Med Chem Lett. 2022. PMID: 35707141 Free PMC article.
36 results