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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1990 1
1992 1
1996 1
1997 1
2001 1
2003 1
2006 1
2007 1
2008 4
2009 1
2013 1
2014 1
2018 1
2020 1
2023 2
2024 0

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18 results

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Page 1
Machine learning-driven multifunctional peptide engineering for sustained ocular drug delivery.
Hsueh HT, Chou RT, Rai U, Liyanage W, Kim YC, Appell MB, Pejavar J, Leo KT, Davison C, Kolodziejski P, Mozzer A, Kwon H, Sista M, Anders NM, Hemingway A, Rompicharla SVK, Edwards M, Pitha I, Hanes J, Cummings MP, Ensign LM. Hsueh HT, et al. Nat Commun. 2023 May 2;14(1):2509. doi: 10.1038/s41467-023-38056-w. Nat Commun. 2023. PMID: 37130851 Free PMC article.
mmeta: An R Package for Multivariate Meta-Analysis.
Luo S, Chen Y, Su X, Chu H. Luo S, et al. J Stat Softw. 2014 Jan 1;56(11):11. J Stat Softw. 2014. PMID: 24904241 Free PMC article.
This paper describes the core features of the R package mmeta, whichimplements the exact posterior inference of odds ratio, relative risk, and risk difference given either a single 2 2 table or multiple 2 2 tables when the risks within the same study are independent or cor …
This paper describes the core features of the R package mmeta, whichimplements the exact posterior inference of odds ratio, relative …
GABAergic neurons and circuits in the pretectal nuclei and the accessory optic system of mammals.
van der Want JJ, Nunes Cardozo JJ, van der Togt C. van der Want JJ, et al. Prog Brain Res. 1992;90:283-305. doi: 10.1016/s0079-6123(08)63619-5. Prog Brain Res. 1992. PMID: 1631302 Review.
A GABAergic projection that originates in the pretectal nuclei is directed towards the superficial layers of the SC in the cat (Appell and Behan, 1990) and rat (Van der Want et al., 1991). A second GABAergic projection derives from the pretectum and reaches the LGN (Cucchi …
A GABAergic projection that originates in the pretectal nuclei is directed towards the superficial layers of the SC in the cat (Appell
Engineered peptide-drug conjugate provides sustained protection of retinal ganglion cells with topical administration in rats.
Hsueh HT, Chou RT, Rai U, Kolodziejski P, Liyanage W, Pejavar J, Mozzer A, Davison C, Appell MB, Kim YC, Leo KT, Kwon H, Sista M, Anders NM, Hemingway A, Rompicharla SVK, Pitha I, Zack DJ, Hanes J, Cummings MP, Ensign LM. Hsueh HT, et al. J Control Release. 2023 Oct;362:371-380. doi: 10.1016/j.jconrel.2023.08.058. Epub 2023 Sep 4. J Control Release. 2023. PMID: 37657693
The role of mitochondria in aging of skeletal muscle.
Figueiredo PA, Mota MP, Appell HJ, Duarte JA. Figueiredo PA, et al. Biogerontology. 2008 Apr;9(2):67-84. doi: 10.1007/s10522-007-9121-7. Epub 2008 Jan 4. Biogerontology. 2008. PMID: 18175203 Review.
Role of TPMT and ITPA variants in mercaptopurine disposition.
Gerbek T, Ebbesen M, Nersting J, Frandsen TL, Appell ML, Schmiegelow K. Gerbek T, et al. Cancer Chemother Pharmacol. 2018 Mar;81(3):579-586. doi: 10.1007/s00280-018-3525-8. Epub 2018 Feb 1. Cancer Chemother Pharmacol. 2018. PMID: 29387964
RESULTS: Median DNA-TG (mDNA-TG) levels were higher in TPMT and ITPA low-activity patients as compared to wildtype patients (TPMT(LA) 549 vs. 364 fmol/g DNA, p = 0.007, ITPA(LA) 465 vs. 387 fmol/g DNA, p = 0.04). mDNA-TG levels were positively correlated to median Ery-TGN (mEry-T …
RESULTS: Median DNA-TG (mDNA-TG) levels were higher in TPMT and ITPA low-activity patients as compared to wildtype patients (TPMT(LA) 549 vs …
Predictive Quantitative Structure-Activity Relationship Modeling of the Antifungal and Antibiotic Properties of Triazolothiadiazine Compounds.
Appell M, Compton DL, Evans KO. Appell M, et al. Methods Protoc. 2020 Dec 27;4(1):2. doi: 10.3390/mps4010002. Methods Protoc. 2020. PMID: 33375476 Free PMC article.
Two or three descriptor models provided validated predictive models for antifungal and antibiotic properties with R (2) values between 0.725 and 0.768 and no outliers. The best models to describe antimicrobial activities include descriptors related to connectivity, electro …
Two or three descriptor models provided validated predictive models for antifungal and antibiotic properties with R (2) values betwee …
Synthesis of (3,4-dimethoxyphenoxy)alkylamino acetamides as orexin-2 receptor antagonists.
Cole AG, Stroke IL, Qin LY, Hussain Z, Simhadri S, Brescia MR, Waksmunski FS, Strohl B, Tellew JE, Williams JP, Saunders J, Appell KC, Henderson I, Webb ML. Cole AG, et al. Bioorg Med Chem Lett. 2008 Oct 15;18(20):5420-3. doi: 10.1016/j.bmcl.2008.09.038. Epub 2008 Sep 12. Bioorg Med Chem Lett. 2008. PMID: 18815029
The discovery and synthesis of a series of (dimethoxyphenoxy)alkylamino acetamides as orexin-2 receptor antagonists from a small-molecule combinatorial library using a high-throughput calcium mobilization functional assay (HEK293-human OX2-R cell line) is described. Active …
The discovery and synthesis of a series of (dimethoxyphenoxy)alkylamino acetamides as orexin-2 receptor antagonists from a small-molecule co …
Apolipoprotein E polymorphism and response to electroconvulsive therapy.
Fisman M, Rabheru K, Hegele RA, Sharma V, Fisman D, Doering M, Appell J. Fisman M, et al. J ECT. 2001 Mar;17(1):11-4. doi: 10.1097/00124509-200103000-00003. J ECT. 2001. PMID: 11281508
Inpatients, out-patients, and day-treatment patients who had received ECT comprised the study group. The 34 patients included met DSM-III-R criteria for affective or schizoaffective disorder. Responder or nonresponder status was assessed using the Clinical Global Inventory …
Inpatients, out-patients, and day-treatment patients who had received ECT comprised the study group. The 34 patients included met DSM-III- …
The Le Bag orthotopic urinary diversion.
Kolettis PN, Klein EA, Novick AC, Winters JC, Appell RA. Kolettis PN, et al. J Urol. 1996 Sep;156(3):926-30. J Urol. 1996. PMID: 8709365 Clinical Trial.
Most patients had mild hyperchloremic metabolic acidosis postoperatively as evidenced by a decrease in median serum bicarbonate level (28 versus 24 mmol./l.). This difference appears to be related to pouch length (r = 0.58, p = 0.0002). CONCLUSIONS: We conclude that the Le …
Most patients had mild hyperchloremic metabolic acidosis postoperatively as evidenced by a decrease in median serum bicarbonate level (28 ve …
18 results