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Opposite alterations of 5-HT2A receptor brain density in subjects with schizophrenia: relevance of radiotracers pharmacological profile.
Diez-Alarcia R, Muguruza C, Rivero G, García-Bea A, Gómez-Vallejo V, Callado LF, Llop J, Martín A, Meana JJ. Diez-Alarcia R, et al. Among authors: martin a. Transl Psychiatry. 2021 May 20;11(1):302. doi: 10.1038/s41398-021-01430-7. Transl Psychiatry. 2021. PMID: 34016955 Free PMC article.
This study investigates 5-HT(2A)R density in the post-mortem prefrontal cortex from subjects with schizophrenia and controls using three radiotracers with a different pharmacological profile. ...A consequent reduction of the inactive 5-HT(2A)R conformation, which is …
This study investigates 5-HT(2A)R density in the post-mortem prefrontal cortex from subjects with schizophrenia and controls using th …
Pharmacokinetic Evaluation of New Drugs Using a Multi-Labelling Approach and PET Imaging: Application to a Drug Candidate with Potential Application in Neuromuscular Disorders.
Passannante R, Gómez-Vallejo V, Sagartzazu-Aizpurua M, Vignau Arsuaga L, Marco-Moreno P, Aldanondo G, Vallejo-Illarramendi A, Aguiar P, Cossío U, Martín A, Bergare J, Kingston L, Elmore CS, Morcillo MA, Ferrón P, Aizpurua JM, Llop J. Passannante R, et al. Among authors: martin a. Biomedicines. 2023 Jan 18;11(2):253. doi: 10.3390/biomedicines11020253. Biomedicines. 2023. PMID: 36830793 Free PMC article.
In vivo imaging of system xc- as a novel approach to monitor multiple sclerosis.
Martín A, Vázquez-Villoldo N, Gómez-Vallejo V, Padro D, Soria FN, Szczupak B, Plaza-García S, Arrieta A, Reese T, Llop J, Domercq M, Matute C. Martín A, et al. Eur J Nucl Med Mol Imaging. 2016 Jun;43(6):1124-38. doi: 10.1007/s00259-015-3275-3. Epub 2015 Dec 10. Eur J Nucl Med Mol Imaging. 2016. PMID: 26659901
METHODS: Longitudinal in vivo magnetic resonance (MRI) and positron emission tomography (PET) imaging studies with 2-[(18)F]Fluoro-2-deoxy-D-glucose ([(18)F]FDG), [(11)C]-(R)-(1-(2-chlorophenyl)-N-methyl-N-1(1-methylpropyl)-3-isoquinolinecarboxamide ([(11)C]PK11195) and (4 …
METHODS: Longitudinal in vivo magnetic resonance (MRI) and positron emission tomography (PET) imaging studies with 2-[(18)F]Fluoro-2-deoxy-D …