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Assessment of Mini-Tablets Coating Uniformity as a Function of Fluid Bed Coater Inlet Conditions.
Turk M, Šibanc R, Dreu R, Frankiewicz M, Sznitowska M. Turk M, et al. Pharmaceutics. 2021 May 18;13(5):746. doi: 10.3390/pharmaceutics13050746. Pharmaceutics. 2021. PMID: 34070006 Free PMC article.
Additionally, coating thickness was evaluated by colorimetric analysis (n = 1000), using a scanner method, and expressed as a hue value. A high correlation (R = 0.993) between inter-tablet variability of hue and UV-Vis results was obtained. ...
Additionally, coating thickness was evaluated by colorimetric analysis (n = 1000), using a scanner method, and expressed as a hue value. A h …
Optimization of a semi-batch tablet coating process for a continuous manufacturing line by design of experiments.
Barimani S, Šibanc R, Kleinebudde P. Barimani S, et al. Int J Pharm. 2018 Mar 25;539(1-2):95-103. doi: 10.1016/j.ijpharm.2018.01.038. Epub 2018 Jan 31. Int J Pharm. 2018. PMID: 29366942
Calibration models were built based on the three center points of the statistical design of experiment resulting in RMSEC of 1.07% of sprayed suspension with R(2) of 0.9989 and Q(2) of 0.9987. Model prediction was possible independent from loading, spray rate and drum rota …
Calibration models were built based on the three center points of the statistical design of experiment resulting in RMSEC of 1.07% of spraye …