Molecular and structural analysis of a continuous birch profilin epitope defined by a monoclonal antibody.
Wiedemann P, Giehl K, Almo SC, Fedorov AA, Girvin M, Steinberger P, Rüdiger M, Ortner M, Sippl M, Dolecek C, Kraft D, Jockusch B, Valenta R.
Wiedemann P, et al.
J Biol Chem. 1996 Nov 22;271(47):29915-21. doi: 10.1074/jbc.271.47.29915.
J Biol Chem. 1996.
PMID: 8939935
Free article.
The exchange of a single amino acid (Gln-47 --> Glu) within the epitope was found to abolish the binding of monoclonal antibody 4A6 to other plant profilins. The NMR analyses of the birch and the nonreactive timothy grass profilin peptides showed that the loss of bindin …
The exchange of a single amino acid (Gln-47 --> Glu) within the epitope was found to abolish the binding of monoclonal antibody 4A6 to ot …