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A pH-responsive nanoparticle targets the neurokinin 1 receptor in endosomes to prevent chronic pain.
Ramírez-García PD, Retamal JS, Shenoy P, Imlach W, Sykes M, Truong N, Constandil L, Pelissier T, Nowell CJ, Khor SY, Layani LM, Lumb C, Poole DP, Lieu T, Stewart GD, Mai QN, Jensen DD, Latorre R, Scheff NN, Schmidt BL, Quinn JF, Whittaker MR, Veldhuis NA, Davis TP, Bunnett NW. Ramírez-García PD, et al. Among authors: mai qn. Nat Nanotechnol. 2019 Dec;14(12):1150-1159. doi: 10.1038/s41565-019-0568-x. Epub 2019 Nov 4. Nat Nanotechnol. 2019. PMID: 31686009 Free PMC article.
A lipid-anchored neurokinin 1 receptor antagonist prolongs pain relief by a three-pronged mechanism of action targeting the receptor at the plasma membrane and in endosomes.
Mai QN, Shenoy P, Quach T, Retamal JS, Gondin AB, Yeatman HR, Aurelio L, Conner JW, Poole DP, Canals M, Nowell CJ, Graham B, Davis TP, Briddon SJ, Hill SJ, Porter CJH, Bunnett NW, Halls ML, Veldhuis NA. Mai QN, et al. J Biol Chem. 2021 Jan-Jun;296:100345. doi: 10.1016/j.jbc.2021.100345. Epub 2021 Jan 28. J Biol Chem. 2021. PMID: 33515548 Free PMC article.
A dengue outbreak on a floating village at Cat Ba Island in Vietnam.
Le Viet T, Choisy M, Bryant JE, Vu Trong D, Pham Quang T, Horby P, Nguyen Tran H, Tran Thi Kieu H, Nguyen Vu T, Nguyen Van K, Le Quynh M, Wertheim HF. Le Viet T, et al. Among authors: le quynh m. BMC Public Health. 2015 Sep 22;15:940. doi: 10.1186/s12889-015-2235-y. BMC Public Health. 2015. PMID: 26395076 Free PMC article.
Missed detections of influenza A(H1)pdm09 by real-time RT-PCR assay due to haemagglutinin sequence mutation, December 2017 to March 2018, northern Viet Nam.
Hoang Vu Mai P, Ung Thi Hong T, Nguyen Le Khanh H, Nguyen Thanh T, Le Thi T, Nguyen Vu S, Nguyen Phuong A, Tran Thi Thu H, Vuong Duc C, Le Quynh M. Hoang Vu Mai P, et al. Among authors: le quynh m. Western Pac Surveill Response J. 2019 Mar 31;10(1):32-38. doi: 10.5365/wpsar.2018.9.3.003. eCollection 2019 Jan-Mar. Western Pac Surveill Response J. 2019. PMID: 31110840 Free PMC article.
15 results