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Page 1
Showing results for eisen xie
Search for Qisen Xie instead (3 results)
Ferroptosis: process and function.
Xie Y, Hou W, Song X, Yu Y, Huang J, Sun X, Kang R, Tang D. Xie Y, et al. Cell Death Differ. 2016 Mar;23(3):369-79. doi: 10.1038/cdd.2015.158. Epub 2016 Jan 22. Cell Death Differ. 2016. PMID: 26794443 Free PMC article. Review.
This process is characterized by the accumulation of lipid peroxidation products and lethal reactive oxygen species (ROS) derived from iron metabolism and can be pharmacologically inhibited by iron chelators (e.g., deferoxamine and desferrioxamine mesylate) and lipi …
This process is characterized by the accumulation of lipid peroxidation products and lethal reactive oxygen species (ROS) derived from ir …
TMEM164 is a new determinant of autophagy-dependent ferroptosis.
Liu J, Liu Y, Wang Y, Li C, Xie Y, Klionsky DJ, Kang R, Tang D. Liu J, et al. Autophagy. 2023 Mar;19(3):945-956. doi: 10.1080/15548627.2022.2111635. Epub 2022 Aug 22. Autophagy. 2023. PMID: 35947500 Free PMC article.
In addition to autophagy's pro-survival effect during nutrient starvation, excessive activation of autophagy machinery can also cause regulated cell death, especially iron-dependent ferroptosis. Here, we report a key role of TMEM164 (transmembrane protein 164) in selective …
In addition to autophagy's pro-survival effect during nutrient starvation, excessive activation of autophagy machinery can also cause regula …
Autophagy promotes ferroptosis by degradation of ferritin.
Hou W, Xie Y, Song X, Sun X, Lotze MT, Zeh HJ 3rd, Kang R, Tang D. Hou W, et al. Autophagy. 2016 Aug 2;12(8):1425-8. doi: 10.1080/15548627.2016.1187366. Epub 2016 May 31. Autophagy. 2016. PMID: 27245739 Free PMC article.
Ferroptosis, a novel form of regulated cell death, is characterized by a production of reactive oxygen species from accumulated iron and lipid peroxidation. However, the relationship between autophagy and ferroptosis at the genetic level remains unclear. ...Knockout or kno …
Ferroptosis, a novel form of regulated cell death, is characterized by a production of reactive oxygen species from accumulated iron …
Ferroptosis: the potential value target in atherosclerosis.
Ouyang S, You J, Zhi C, Li P, Lin X, Tan X, Ma W, Li L, Xie W. Ouyang S, et al. Cell Death Dis. 2021 Aug 10;12(8):782. doi: 10.1038/s41419-021-04054-3. Cell Death Dis. 2021. PMID: 34376636 Free PMC article. Review.
The forms and mechanisms of cell death in AS have recently been elucidated. Among them, ferroptosis, an iron-dependent form of necrosis that is characterized by oxidative damage to phospholipids, promotes AS by accelerating endothelial dysfunction in lipid peroxidation. Mo …
The forms and mechanisms of cell death in AS have recently been elucidated. Among them, ferroptosis, an iron-dependent form of necros …
Molecular Mechanisms of Ferroptosis and Relevance to Cardiovascular Disease.
Xie LH, Fefelova N, Pamarthi SH, Gwathmey JK. Xie LH, et al. Cells. 2022 Sep 1;11(17):2726. doi: 10.3390/cells11172726. Cells. 2022. PMID: 36078133 Free PMC article. Review.
Ferroptosis has recently been demonstrated to be a novel regulated non-apoptotic cell death characterized by iron-dependence and the accumulation of lipid peroxidation that results in membrane damage. Excessive iron induces ferroptosis by promoting the generation of …
Ferroptosis has recently been demonstrated to be a novel regulated non-apoptotic cell death characterized by iron-dependence and the …
Ferroptosis in Rheumatoid Arthritis: A Potential Therapeutic Strategy.
Zhao T, Yang Q, Xi Y, Xie Z, Shen J, Li Z, Li Z, Qin D. Zhao T, et al. Front Immunol. 2022 Feb 2;13:779585. doi: 10.3389/fimmu.2022.779585. eCollection 2022. Front Immunol. 2022. PMID: 35185879 Free PMC article. Review.
Ferroptosis is one of the newly discovered forms of cell-regulated death characterized by iron-dependent lipid peroxidation. Extensive research has focused on the roles of ferroptosis in tumors, blood diseases, and neurological diseases. ...
Ferroptosis is one of the newly discovered forms of cell-regulated death characterized by iron-dependent lipid peroxidation. Extensiv …
New Insights into the Role of Ferritin in Iron Homeostasis and Neurodegenerative Diseases.
Zhang N, Yu X, Xie J, Xu H. Zhang N, et al. Mol Neurobiol. 2021 Jun;58(6):2812-2823. doi: 10.1007/s12035-020-02277-7. Epub 2021 Jan 28. Mol Neurobiol. 2021. PMID: 33507490 Review.
Ferritin is a hollow iron storage protein composed of 24 subunits of two types, ferritin heavy chain (FTH) and ferritin light chain (FTL), which plays an important role in maintaining iron homeostasis. Recently, the discovery of extracellular ferritin and ferritin i …
Ferritin is a hollow iron storage protein composed of 24 subunits of two types, ferritin heavy chain (FTH) and ferritin light chain ( …
The role of ferroptosis in metabolic diseases.
Xie L, Fang B, Zhang C. Xie L, et al. Biochim Biophys Acta Mol Cell Res. 2023 Aug;1870(6):119480. doi: 10.1016/j.bbamcr.2023.119480. Epub 2023 Apr 29. Biochim Biophys Acta Mol Cell Res. 2023. PMID: 37127193 Review.
Ferroptosis is a novel form of programmed cell death driven by iron-dependent lipid peroxidation, which was discovered in recent years. ...
Ferroptosis is a novel form of programmed cell death driven by iron-dependent lipid peroxidation, which was discovered in recent year …
Ferroptosis and Cancer Immunotherapy.
Yin J, Meng X, Peng L, Xie W, Liu X, He W, Li S. Yin J, et al. Curr Mol Med. 2023;23(5):401-409. doi: 10.2174/1566524022666220509124608. Curr Mol Med. 2023. PMID: 35579155 Review.
As a nonapoptotic cell death process and owning to the characteristics of iron-dependent lipid peroxide accumulation, ferroptosis has become a new target of tumor treatment. ...Meantime, immune cells release immunostimulatory cytokines including TNF-alpha and IFN-gamma to …
As a nonapoptotic cell death process and owning to the characteristics of iron-dependent lipid peroxide accumulation, ferroptosis has …
Multifaceted role of ferroptosis in cardiovascular disease.
Li C, Zhu X, Chen J, Xie X, Liang S, Liu X, Gong Q, Guo J. Li C, et al. Acta Biochim Biophys Sin (Shanghai). 2023 Feb 25;55(2):183-193. doi: 10.3724/abbs.2023019. Acta Biochim Biophys Sin (Shanghai). 2023. PMID: 36815377 Free PMC article. Review.
Ferroptosis is a newly identified form of non-apoptotic cell death characterised primarily by iron-dependent lipid peroxidation. It differs morphologically, biochemically, and genetically from other forms of cell death, such as apoptosis, autophagy, and necrosis. Although …
Ferroptosis is a newly identified form of non-apoptotic cell death characterised primarily by iron-dependent lipid peroxidation. It d …
1,998 results