Intragraft memory-like CD127hiCD4+Foxp3+ Tregs maintain transplant tolerance.
Zhao Y, Nicholson L, Wang H, Qian YW, Hawthorne WJ, Jimenez-Vera E, Gloss BS, Lai J, Thomas A, Chew YV, Burns H, Zhang GY, Wang YM, Rogers NM, Zheng G, Yi S, Alexander SI, O'Connell PJ, Hu M.
Zhao Y, et al.
JCI Insight. 2024 Feb 13;9(6):e169119. doi: 10.1172/jci.insight.169119.
JCI Insight. 2024.
PMID: 38516885
Free article.
A subpopulation of CD127hi Tregs with memory features were found in lymphoid organs, presented in high proportions within long-surviving islet grafts, and had a transcriptomic and phenotypic profile similar to tissue Tregs. ...
A subpopulation of CD127hi Tregs with memory features were found in lymphoid organs, presented in high proportions within long-surviv …