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Pivotal role for two electron reduction in 2,3-dimethoxy-1,4-naphthoquinone and 2-methyl-1,4-naphthoquinone metabolism and kinetics in vivo that prevents liver redox stress.
Parry JD, Pointon AV, Lutz U, Teichert F, Charlwood JK, Chan PH, Athersuch TJ, Taylor EL, Singh R, Luo J, Phillips KM, Vetillard A, Lyon JJ, Keun HC, Lutz WK, Gant TW. Parry JD, et al. Among authors: chan ph. Chem Res Toxicol. 2009 Apr;22(4):717-25. doi: 10.1021/tx800472z. Chem Res Toxicol. 2009. PMID: 19338340