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Year Number of Results
2009 1
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2013 1
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Page 1
Structural and biological characterization of pAC65, a macrocyclic peptide that blocks PD-L1 with equivalent potency to the FDA-approved antibodies.
Rodriguez I, Kocik-Krol J, Skalniak L, Musielak B, Wisniewska A, Ciesiołkiewicz A, Berlicki Ł, Plewka J, Grudnik P, Stec M, Siedlar M, Holak TA, Magiera-Mularz K. Rodriguez I, et al. Among authors: grudnik p. Mol Cancer. 2023 Sep 7;22(1):150. doi: 10.1186/s12943-023-01853-4. Mol Cancer. 2023. PMID: 37679783 Free PMC article.
Crystal Structure of Kluyveromyces lactis Glucokinase (KlGlk1).
Zak KM, Kalińska M, Wątor E, Kuśka K, Krutyhołowa R, Dubin G, Popowicz GM, Grudnik P. Zak KM, et al. Among authors: grudnik p. Int J Mol Sci. 2019 Sep 28;20(19):4821. doi: 10.3390/ijms20194821. Int J Mol Sci. 2019. PMID: 31569356 Free PMC article.
Development of a novel, high-affinity ssDNA trypsin inhibitor.
Malicki S, Ksiazek M, Majewski P, Pecak A, Mydel P, Grudnik P, Dubin G. Malicki S, et al. Among authors: grudnik p. J Enzyme Inhib Med Chem. 2019 Dec;34(1):638-643. doi: 10.1080/14756366.2019.1569648. J Enzyme Inhib Med Chem. 2019. PMID: 30727784 Free PMC article.
E2/E3-independent ubiquitin-like protein conjugation by Urm1 is directly coupled to cysteine persulfidation.
Ravichandran KE, Kaduhr L, Skupien-Rabian B, Shvetsova E, Sokołowski M, Krutyhołowa R, Kwasna D, Brachmann C, Lin S, Guzman Perez S, Wilk P, Kösters M, Grudnik P, Jankowska U, Leidel SA, Schaffrath R, Glatt S. Ravichandran KE, et al. Among authors: grudnik p. EMBO J. 2022 Oct 17;41(20):e111318. doi: 10.15252/embj.2022111318. Epub 2022 Sep 14. EMBO J. 2022. PMID: 36102610 Free PMC article.
Bioactive Macrocyclic Inhibitors of the PD-1/PD-L1 Immune Checkpoint.
Magiera-Mularz K, Skalniak L, Zak KM, Musielak B, Rudzinska-Szostak E, Berlicki Ł, Kocik J, Grudnik P, Sala D, Zarganes-Tzitzikas T, Shaabani S, Dömling A, Dubin G, Holak TA. Magiera-Mularz K, et al. Among authors: grudnik p. Angew Chem Int Ed Engl. 2017 Oct 23;56(44):13732-13735. doi: 10.1002/anie.201707707. Epub 2017 Sep 26. Angew Chem Int Ed Engl. 2017. PMID: 28881104 Free PMC article.
Human and mouse PD-L1: similar molecular structure, but different druggability profiles.
Magiera-Mularz K, Kocik J, Musielak B, Plewka J, Sala D, Machula M, Grudnik P, Hajduk M, Czepiel M, Siedlar M, Holak TA, Skalniak L. Magiera-Mularz K, et al. Among authors: grudnik p. iScience. 2020 Dec 24;24(1):101960. doi: 10.1016/j.isci.2020.101960. eCollection 2021 Jan 22. iScience. 2020. PMID: 33437940 Free PMC article.
32 results