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Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease.
Ridker PM, Everett BM, Thuren T, MacFadyen JG, Chang WH, Ballantyne C, Fonseca F, Nicolau J, Koenig W, Anker SD, Kastelein JJP, Cornel JH, Pais P, Pella D, Genest J, Cifkova R, Lorenzatti A, Forster T, Kobalava Z, Vida-Simiti L, Flather M, Shimokawa H, Ogawa H, Dellborg M, Rossi PRF, Troquay RPT, Libby P, Glynn RJ; CANTOS Trial Group. Ridker PM, et al. N Engl J Med. 2017 Sep 21;377(12):1119-1131. doi: 10.1056/NEJMoa1707914. Epub 2017 Aug 27. N Engl J Med. 2017. PMID: 28845751 Free article. Clinical Trial.
METHODS: We conducted a randomized, double-blind trial of canakinumab, a therapeutic monoclonal antibody targeting interleukin-1beta, involving 10,061 patients with previous myocardial infarction and a high-sensitivity C-reactive protein level of 2 mg or more per liter. Th …
METHODS: We conducted a randomized, double-blind trial of canakinumab, a therapeutic monoclonal antibody targeting interleukin-1beta, involv …
Conflict of Interest Disclosures.
[No authors listed] [No authors listed] Global Spine J. 2024 May;14(4_suppl):690S-714S. doi: 10.1177/21925682241245615. Global Spine J. 2024. PMID: 38726630 Free PMC article. No abstract available.
Purification and characterization of the enzyme cholesterol oxidase from a new isolate of Streptomyces sp.
Praveen V, Srivastava A, Tripathi CK. Praveen V, et al. Appl Biochem Biotechnol. 2011 Nov;165(5-6):1414-26. doi: 10.1007/s12010-011-9360-6. Epub 2011 Sep 10. Appl Biochem Biotechnol. 2011. PMID: 21909628
Specific activity of the purified enzyme was found to be 20 U/mg with a 55 kDa molecular mass. The enzyme was stable at pH 7.2 and 50 C. The enzyme activity was inhibited in the presence of Pb(2+), Ag(2+), Hg(2+), and Zn(2+) and enhanced in the presence of Mn(2+). ...
Specific activity of the purified enzyme was found to be 20 U/mg with a 55 kDa molecular mass. The enzyme was stable at pH 7.2 and 50 C …
Enhanced vermicomposting of rice straw and pressmud with biogas slurry employing Eisenia fetida: Production, characterization, growth, and toxicological risk assessment.
Srivastava PK, Tiwari GN, Sinha ASK. Srivastava PK, et al. J Environ Manage. 2024 Feb 14;352:120032. doi: 10.1016/j.jenvman.2024.120032. Epub 2024 Jan 6. J Environ Manage. 2024. PMID: 38184874
The characterization, elemental analysis, and toxicological risk assessment of derived vermimanure were carried out using various analytical tools, such as an organic elemental analyzer such as CHNS, FT-IR, FESEM-EDXA, XPS, and ICP-OES. The pH, electrical conductivity, and C …
The characterization, elemental analysis, and toxicological risk assessment of derived vermimanure were carried out using various analytical …