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Tigilanol tiglate is an oncolytic small molecule that induces immunogenic cell death and enhances the response of both target and non-injected tumors to immune checkpoint blockade.
Cullen JK, Yap PY, Ferguson B, Bruce ZC, Koyama M, Handoko H, Hendrawan K, Simmons JL, Brooks KM, Johns J, Wilson ES, de Souza MMA, Broit N, Stewart P, Shelley D, McMahon T, Ogbourne SM, Nguyen TH, Lim YC, Pagani A, Appendino G, Gordon VA, Reddell PW, Boyle GM, Parsons PG. Cullen JK, et al. Among authors: stewart p. J Immunother Cancer. 2024 Apr 24;12(4):e006602. doi: 10.1136/jitc-2022-006602. J Immunother Cancer. 2024. PMID: 38658031 Free PMC article.
Cloning of the crustacean hyperglycemic hormone and evidence for molt-inhibiting hormone within the central nervous system of the blue crab Portunus pelagicus.
Stewart MJ, Stewart P, Sroyraya M, Soonklang N, Cummins SF, Hanna PJ, Duan W, Sobhon P. Stewart MJ, et al. Among authors: stewart p. Comp Biochem Physiol A Mol Integr Physiol. 2013 Feb;164(2):276-90. doi: 10.1016/j.cbpa.2012.10.029. Epub 2012 Oct 25. Comp Biochem Physiol A Mol Integr Physiol. 2013. PMID: 23103673