Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1914 1
1930 1
1955 1
1959 1
1963 1
1968 2
1970 2
1972 1
1975 7
1976 10
1977 9
1978 9
1979 7
1980 12
1981 12
1982 10
1983 8
1984 14
1985 22
1986 18
1987 23
1988 14
1989 21
1990 23
1991 30
1992 22
1993 28
1994 25
1995 29
1996 36
1997 43
1998 35
1999 48
2000 35
2001 47
2002 53
2003 63
2004 67
2005 71
2006 82
2007 98
2008 106
2009 115
2010 159
2011 147
2012 196
2013 183
2014 201
2015 218
2016 244
2017 266
2018 322
2019 358
2020 381
2021 381
2022 378
2023 366
2024 156

Text availability

Article attribute

Article type

Publication date

Search Results

4,632 results

Results by year

Filters applied: . Clear all
The following term was not found in PubMed: Vershuuren
Page 1
Pim Kinases: Important Regulators of Cardiovascular Disease.
Nock S, Karim E, Unsworth AJ. Nock S, et al. Int J Mol Sci. 2023 Jul 18;24(14):11582. doi: 10.3390/ijms241411582. Int J Mol Sci. 2023. PMID: 37511341 Free PMC article. Review.
Pim Kinases; Pim-1, Pim-2, and Pim-3, are a family of constitutively active serine/threonine kinases, widely associated with cell survival, proliferation, and migration. ...In this review, we discuss what is known about Pim kinase expression and …
Pim Kinases; Pim-1, Pim-2, and Pim-3, are a family of constitutively active serine/threonine kinases, widely ass …
PIM Kinases in Multiple Myeloma.
Wu J, Chu E, Kang Y. Wu J, et al. Cancers (Basel). 2021 Aug 26;13(17):4304. doi: 10.3390/cancers13174304. Cancers (Basel). 2021. PMID: 34503111 Free PMC article. Review.
This review provides a comprehensive overview of the PIM kinase pathways and the current research status of the development of PIM kinase inhibitors for the treatment of MM. Additionally, the combinatorial effects of the PIM kinase inhibitors with other targe …
This review provides a comprehensive overview of the PIM kinase pathways and the current research status of the development of PIM …
Targeting Pim kinases in hematological cancers: molecular and clinical review.
Bellon M, Nicot C. Bellon M, et al. Mol Cancer. 2023 Jan 25;22(1):18. doi: 10.1186/s12943-023-01721-1. Mol Cancer. 2023. PMID: 36694243 Free PMC article. Review.
Decades of research has recognized a solid role for Pim kinases in lymphoproliferative disorders. Often up-regulated following JAK/STAT and tyrosine kinase receptor signaling, Pim kinases regulate cell proliferation, survival, metabolism, cellular trafficking and si …
Decades of research has recognized a solid role for Pim kinases in lymphoproliferative disorders. Often up-regulated following JAK/ST …
The role of Pim kinase in immunomodulation.
Liu Z, Han M, Ding K, Fu R. Liu Z, et al. Am J Cancer Res. 2020 Dec 1;10(12):4085-4097. eCollection 2020. Am J Cancer Res. 2020. PMID: 33414987 Free PMC article. Review.
Pim kinase, which has three isozymes (Pim-1, Pim-2 and Pim-3), is a serine/threonine kinase abnormally expressed in many cancers. ...In recent years, researches verified the role of Pim kinase in immunomodulation. The mechanisms by which Pim …
Pim kinase, which has three isozymes (Pim-1, Pim-2 and Pim-3), is a serine/threonine kinase abnormally expressed …
Targeting PIM Kinases to Improve the Efficacy of Immunotherapy.
Clements AN, Warfel NA. Clements AN, et al. Cells. 2022 Nov 21;11(22):3700. doi: 10.3390/cells11223700. Cells. 2022. PMID: 36429128 Free PMC article. Review.
The role of PIM in immune evasion has sparked interest in examining the effect of PIM inhibition in combination with immunotherapy. This review focuses on the role of PIM kinases in regulating immune cell populations, how PIM modulates the immune tumor …
The role of PIM in immune evasion has sparked interest in examining the effect of PIM inhibition in combination with immunothe …
PIM kinase inhibitors: Structural and pharmacological perspectives.
Asati V, Mahapatra DK, Bharti SK. Asati V, et al. Eur J Med Chem. 2019 Jun 15;172:95-108. doi: 10.1016/j.ejmech.2019.03.050. Epub 2019 Mar 23. Eur J Med Chem. 2019. PMID: 30954777 Review.
The PIM kinase, also known as serine/threonine kinase plays an important role in cancer biology and is found in three different isoforms namely PIM-1, PIM-2, and PIM-3. ...Several medicinally privileged heterocyclic ring scaffolds such as pyrrole, pyri …
The PIM kinase, also known as serine/threonine kinase plays an important role in cancer biology and is found in three different isofo …
PIM kinases: From survival factors to regulators of cell motility.
Santio NM, Koskinen PJ. Santio NM, et al. Int J Biochem Cell Biol. 2017 Dec;93:74-85. doi: 10.1016/j.biocel.2017.10.016. Epub 2017 Nov 3. Int J Biochem Cell Biol. 2017. PMID: 29108877 Review.
Since high PIM expression levels have been connected to cancer progression and poor patient survival, PIM kinases have become attractive targets for drug development. Many downstream targets have also been identified, through which PIM kinases promote cell su …
Since high PIM expression levels have been connected to cancer progression and poor patient survival, PIM kinases have become …
PIM Kinase as an Executional Target in Cancer.
Zhang X, Song M, Kundu JK, Lee MH, Liu ZZ. Zhang X, et al. J Cancer Prev. 2018 Sep;23(3):109-116. doi: 10.15430/JCP.2018.23.3.109. Epub 2018 Sep 30. J Cancer Prev. 2018. PMID: 30370255 Free PMC article. Review.
The aberrant expression and/or activation of PIM kinases in various cancers follow an isoform-specific pattern. ...This review sheds light on the signaling pathways involved in the PIM kinase regulation and current status of developing PIM kinase inhibitors a …
The aberrant expression and/or activation of PIM kinases in various cancers follow an isoform-specific pattern. ...This review sheds …
Pim kinases in hematological malignancies: where are we now and where are we going?
Mondello P, Cuzzocrea S, Mian M. Mondello P, et al. J Hematol Oncol. 2014 Dec 10;7:95. doi: 10.1186/s13045-014-0095-z. J Hematol Oncol. 2014. PMID: 25491234 Free PMC article. Review.
The proviral insertion in murine (PIM) lymphoma proteins are a serine/threonine kinase family composed of three isoformes: Pim-1, Pim-2 and Pim-3. ...Novel molecules inhibiting Pim kinases have been evaluated in preclinical studies, demonstratin …
The proviral insertion in murine (PIM) lymphoma proteins are a serine/threonine kinase family composed of three isoformes: Pim …
Topical advances in PIM kinases and their inhibitors: Medicinal chemistry perspectives.
Walhekar V, Bagul C, Kumar D, Muthal A, Achaiah G, Kulkarni R. Walhekar V, et al. Biochim Biophys Acta Rev Cancer. 2022 May;1877(3):188725. doi: 10.1016/j.bbcan.2022.188725. Epub 2022 Apr 1. Biochim Biophys Acta Rev Cancer. 2022. PMID: 35367531 Review.
PIM kinases have now been considered as limelight target for the discovery of new molecules as novel anticancer agents as no drug is in the market targeting PIM kinases. ...The present comprehensive review intends to cover biological and the structural aspects of …
PIM kinases have now been considered as limelight target for the discovery of new molecules as novel anticancer agents as no drug is …
4,632 results