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The following term was not found in PubMed: Lozou
Page 1
Essential Role of Loop Dynamics in Type II NRPS Biomolecular Recognition.
Corpuz JC, Patel A, Davis TD, Podust LM, McCammon JA, Burkart MD. Corpuz JC, et al. ACS Chem Biol. 2022 Oct 21;17(10):2890-2898. doi: 10.1021/acschembio.2c00523. Epub 2022 Sep 29. ACS Chem Biol. 2022. PMID: 36173802 Free PMC article.
Specifically, we determined X-ray crystal structures of a type II PCP crosslinked to its cognate A domain, PigG and PigI, and of PigG crosslinked to a non-cognate PigI homologue, PltF. ...
Specifically, we determined X-ray crystal structures of a type II PCP crosslinked to its cognate A domain, PigG and PigI, and of PigG …
Expression, crystallization and preliminary crystallographic data analysis of PigI, a putative L-prolyl-AMP ligase from the prodigiosin synthetic pathway in Serratia.
Han N, Ran T, Lou X, Gao Y, He J, Tang L, Xu D, Wang W. Han N, et al. Acta Crystallogr F Struct Biol Commun. 2014 May;70(Pt 5):624-7. doi: 10.1107/S2053230X14005780. Epub 2014 Apr 17. Acta Crystallogr F Struct Biol Commun. 2014. PMID: 24817724 Free PMC article.
The first step for the synthesis of MBC is the activation of L-proline by PigI, but its catalytic mechanism has remained elusive. To elucidate its mechanism, recombinant PigI was purified and crystallized. ...
The first step for the synthesis of MBC is the activation of L-proline by PigI, but its catalytic mechanism has remained elusive. To …
Body mass index and risk of cancer in young women.
Dikaiou P, Edqvist J, Lagergren J, Adiels M, Björck L, Rosengren A. Dikaiou P, et al. Sci Rep. 2024 Mar 15;14(1):6245. doi: 10.1038/s41598-024-56899-1. Sci Rep. 2024. PMID: 38485791 Free PMC article.
In silico exploration of Serratia sp. BRL41 genome for detecting prodigiosin Biosynthetic Gene Cluster (BGC) and in vitro antimicrobial activity assessment of secreted prodigiosin.
Boby F, Bhuiyan MNH, Saha BK, Dey SS, Saha AK, Islam MJ, Bashera MA, Moulick SP, Jahan F, Zaman MAU, Chowdhury SF, Naser SR, Khan MS, Sarkar MMH. Boby F, et al. PLoS One. 2023 Nov 15;18(11):e0294054. doi: 10.1371/journal.pone.0294054. eCollection 2023. PLoS One. 2023. PMID: 37967102 Free PMC article.
"Prodigiosin NRPS", among the 10 analyzed gene clusters, showed 100% similarity with query sequences where pigC, pigH, pigI, and pigJ were identified as fundamental genes for prodigiosin biosynthesis. ...
"Prodigiosin NRPS", among the 10 analyzed gene clusters, showed 100% similarity with query sequences where pigC, pigH, pigI, and pigJ …
Manipulating Protein-Protein Interactions in Nonribosomal Peptide Synthetase Type II Peptidyl Carrier Proteins.
Jaremko MJ, Lee DJ, Patel A, Winslow V, Opella SJ, McCammon JA, Burkart MD. Jaremko MJ, et al. Biochemistry. 2017 Oct 10;56(40):5269-5273. doi: 10.1021/acs.biochem.7b00884. Epub 2017 Oct 2. Biochemistry. 2017. PMID: 28920687 Free PMC article.
Three peptidyl carrier proteins, PigG, PltL, and RedO, in addition to their cognate adenylation domains, PigI, PltF, and RedM, were investigated for their cross-species activity. ...
Three peptidyl carrier proteins, PigG, PltL, and RedO, in addition to their cognate adenylation domains, PigI, PltF, and RedM, were i …
Crystal structure of MBP-PigG fusion protein and the essential function of PigG in the prodigiosin biosynthetic pathway in Serratia marcescens FS14.
Zhang F, Wei Q, Tong H, Xu D, Wang W, Ran T. Zhang F, et al. Int J Biol Macromol. 2017 Jun;99:394-400. doi: 10.1016/j.ijbiomac.2017.02.088. Epub 2017 Mar 1. Int J Biol Macromol. 2017. PMID: 28258005
Prodigiosin, a tripyrrole red pigment is synthesized by Serratia and some other microbes through a bifurcated biosynthesis pathway; MBC (4-methoxy-2,2'-bipyrrole-5-carbaldehyde) and MAP (2-methyl-3-n-amyl-pyrrole) are synthesized separately and then condensed by PigC to form prod …
Prodigiosin, a tripyrrole red pigment is synthesized by Serratia and some other microbes through a bifurcated biosynthesis pathway; MBC (4-m …
Biosynthesis of the red antibiotic, prodigiosin, in Serratia: identification of a novel 2-methyl-3-n-amyl-pyrrole (MAP) assembly pathway, definition of the terminal condensing enzyme, and implications for undecylprodigiosin biosynthesis in Streptomyces.
Williamson NR, Simonsen HT, Ahmed RA, Goldet G, Slater H, Woodley L, Leeper FJ, Salmond GP. Williamson NR, et al. Mol Microbiol. 2005 May;56(4):971-89. doi: 10.1111/j.1365-2958.2005.04602.x. Mol Microbiol. 2005. PMID: 15853884 Free article.
Based on these results we assign specific roles in the biosynthesis of MBC to the following Pig proteins: PigI, PigG, PigA, PigJ, PigH, PigM, PigF and PigN. We report a novel pathway for the biosynthesis of MAP, involving PigD, PigE and PigB. ...
Based on these results we assign specific roles in the biosynthesis of MBC to the following Pig proteins: PigI, PigG, PigA, PigJ, Pig …
Protein assembly line components in prodigiosin biosynthesis: characterization of PigA,G,H,I,J.
Garneau-Tsodikova S, Dorrestein PC, Kelleher NL, Walsh CT. Garneau-Tsodikova S, et al. J Am Chem Soc. 2006 Oct 4;128(39):12600-1. doi: 10.1021/ja063611l. J Am Chem Soc. 2006. PMID: 17002325
At first, pyrrole ring A is formed on the peptidyl carrier protein PigG by one of two possible ways: (i) by action of the adenylation domain PigI that transforms l-proline into l-prolyl-AMP and by the flavoprotein dehydrogenase PigA responsible for the four-electron oxidat …
At first, pyrrole ring A is formed on the peptidyl carrier protein PigG by one of two possible ways: (i) by action of the adenylation domain …
19 results