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Sub-millisecond conformational dynamics of the A2A adenosine receptor revealed by single-molecule FRET.
Maslov I, Volkov O, Khorn P, Orekhov P, Gusach A, Kuzmichev P, Gerasimov A, Luginina A, Coucke Q, Bogorodskiy A, Gordeliy V, Wanninger S, Barth A, Mishin A, Hofkens J, Cherezov V, Gensch T, Hendrix J, Borshchevskiy V. Maslov I, et al. Among authors: orekhov p. Commun Biol. 2023 Apr 3;6(1):362. doi: 10.1038/s42003-023-04727-z. Commun Biol. 2023. PMID: 37012383 Free PMC article.
Molecular mechanism of light-driven sodium pumping.
Kovalev K, Astashkin R, Gushchin I, Orekhov P, Volkov D, Zinovev E, Marin E, Rulev M, Alekseev A, Royant A, Carpentier P, Vaganova S, Zabelskii D, Baeken C, Sergeev I, Balandin T, Bourenkov G, Carpena X, Boer R, Maliar N, Borshchevskiy V, Büldt G, Bamberg E, Gordeliy V. Kovalev K, et al. Among authors: orekhov p. Nat Commun. 2020 May 1;11(1):2137. doi: 10.1038/s41467-020-16032-y. Nat Commun. 2020. PMID: 32358514 Free PMC article.
Mechanisms of Formation, Structure, and Dynamics of Lipoprotein Discs Stabilized by Amphiphilic Copolymers: A Comprehensive Review.
Orekhov PS, Bozdaganyan ME, Voskoboynikova N, Mulkidjanian AY, Karlova MG, Yudenko A, Remeeva A, Ryzhykau YL, Gushchin I, Gordeliy VI, Sokolova OS, Steinhoff HJ, Kirpichnikov MP, Shaitan KV. Orekhov PS, et al. Nanomaterials (Basel). 2022 Jan 23;12(3):361. doi: 10.3390/nano12030361. Nanomaterials (Basel). 2022. PMID: 35159706 Free PMC article. Review.
CPE-DB: An Open Database of Chemical Penetration Enhancers.
Vasyuchenko EP, Orekhov PS, Armeev GA, Bozdaganyan ME. Vasyuchenko EP, et al. Among authors: orekhov ps. Pharmaceutics. 2021 Jan 7;13(1):66. doi: 10.3390/pharmaceutics13010066. Pharmaceutics. 2021. PMID: 33430205 Free PMC article.
Molecular model of a sensor of two-component signaling system.
Ryzhykau YL, Orekhov PS, Rulev MI, Vlasov AV, Melnikov IA, Volkov DA, Nikolaev MY, Zabelskii DV, Murugova TN, Chupin VV, Rogachev AV, Gruzinov AY, Svergun DI, Brennich ME, Gushchin IY, Soler-Lopez M, Bothe A, Büldt G, Leonard G, Engelhard M, Kuklin AI, Gordeliy VI. Ryzhykau YL, et al. Among authors: orekhov ps. Sci Rep. 2021 May 24;11(1):10774. doi: 10.1038/s41598-021-89613-6. Sci Rep. 2021. PMID: 34031444 Free PMC article.
Structural basis for receptor selectivity and inverse agonism in S1P5 receptors.
Lyapina E, Marin E, Gusach A, Orekhov P, Gerasimov A, Luginina A, Vakhrameev D, Ergasheva M, Kovaleva M, Khusainov G, Khorn P, Shevtsov M, Kovalev K, Bukhdruker S, Okhrimenko I, Popov P, Hu H, Weierstall U, Liu W, Cho Y, Gushchin I, Rogachev A, Bourenkov G, Park S, Park G, Hyun HJ, Park J, Gordeliy V, Borshchevskiy V, Mishin A, Cherezov V. Lyapina E, et al. Among authors: orekhov p. Nat Commun. 2022 Aug 12;13(1):4736. doi: 10.1038/s41467-022-32447-1. Nat Commun. 2022. PMID: 35961984 Free PMC article.
High-pressure crystallography shows noble gas intervention into protein-lipid interaction and suggests a model for anaesthetic action.
Melnikov I, Orekhov P, Rulev M, Kovalev K, Astashkin R, Bratanov D, Ryzhykau Y, Balandin T, Bukhdruker S, Okhrimenko I, Borshchevskiy V, Bourenkov G, Mueller-Dieckmann C, van der Linden P, Carpentier P, Leonard G, Gordeliy V, Popov A. Melnikov I, et al. Among authors: orekhov p. Commun Biol. 2022 Apr 14;5(1):360. doi: 10.1038/s42003-022-03233-y. Commun Biol. 2022. PMID: 35422073 Free PMC article.
Structural insights into the effects of glycerol on ligand binding to cytochrome P450.
Bukhdruker S, Varaksa T, Orekhov P, Grabovec I, Marin E, Kapranov I, Kovalev K, Astashkin R, Kaluzhskiy L, Ivanov A, Mishin A, Rogachev A, Gordeliy V, Gilep A, Strushkevich N, Borshchevskiy V. Bukhdruker S, et al. Among authors: orekhov p. Acta Crystallogr D Struct Biol. 2023 Jan 1;79(Pt 1):66-77. doi: 10.1107/S2059798322011019. Epub 2023 Jan 1. Acta Crystallogr D Struct Biol. 2023. PMID: 36601808
27 results