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Page 1
A biased ligand for OXE-R uncouples Gα and Gβγ signaling within a heterotrimer.
Nat Chem Biol. 2012 Jul;8(7):631-8. doi: 10.1038/nchembio.962. Epub 2012 May 27.
Nat Chem Biol. 2012.
PMID: 22634634
An access to aza-Freidinger lactams and E-locked analogs.
Ottersbach PA, Schmitz J, Schnakenburg G, Gütschow M.
Ottersbach PA, et al.
Org Lett. 2013 Feb 1;15(3):448-51. doi: 10.1021/ol3030583. Epub 2013 Jan 15.
Org Lett. 2013.
PMID: 23320486
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A biased non-Gαi OXE-R antagonist demonstrates that Gαi protein subunit is not directly involved in neutrophil, eosinophil, and monocyte activation by 5-oxo-ETE.
Konya V, Blättermann S, Jandl K, Platzer W, Ottersbach PA, Marsche G, Gütschow M, Kostenis E, Heinemann A.
Konya V, et al.
J Immunol. 2014 May 15;192(10):4774-82. doi: 10.4049/jimmunol.1302013. Epub 2014 Apr 14.
J Immunol. 2014.
PMID: 24733850
Clinical Trial.
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Induction of chirality: experimental evidence of atropisomerism in azapeptides.
Ottersbach PA, Schnakenburg G, Gütschow M.
Ottersbach PA, et al.
Chem Commun (Camb). 2012 Jun 11;48(46):5772-4. doi: 10.1039/c2cc31161e. Epub 2012 May 2.
Chem Commun (Camb). 2012.
PMID: 22552375
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Direct formation of ring-fused 1,3-thiazine-2,4-dithiones from aromatic o-amino carboxylic acids: observation of a carbon disulfide mediated thionation.
Ottersbach PA, Elsinghorst PW, Häcker HG, Gütschow M.
Ottersbach PA, et al.
Org Lett. 2010 Aug 20;12(16):3662-5. doi: 10.1021/ol101471g.
Org Lett. 2010.
PMID: 20666472
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2-Amino- and 2-alkylthio-4H-3,1-benzothiazin-4-ones: synthesis, interconversion and enzyme inhibitory activities.
Häcker HG, Grundmann F, Lohr F, Ottersbach PA, Zhou J, Schnakenburg G, Gütschow M.
Häcker HG, et al. Among authors: ottersbach pa.
Molecules. 2009 Jan 14;14(1):378-402. doi: 10.3390/molecules14010378.
Molecules. 2009.
PMID: 19145216
Free PMC article.
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