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Pancreatic islet protection at the expense of secretory function involves serine-linked mitochondrial one-carbon metabolism.
Pelligra A, Mrugala J, Griess K, Kirschner P, Nortmann O, Bartosinska B, Köster A, Krupenko NI, Gebel D, Westhoff P, Steckel B, Eberhard D, Herebian D, Belgardt BF, Schrader J, Weber APM, Krupenko SA, Lammert E. Pelligra A, et al. Among authors: kirschner p. Cell Rep. 2023 Jun 27;42(6):112615. doi: 10.1016/j.celrep.2023.112615. Epub 2023 Jun 8. Cell Rep. 2023. PMID: 37294632 Free PMC article.
Carnosinase-1 Knock-Out Reduces Kidney Fibrosis in Type-1 Diabetic Mice on High Fat Diet.
Pfeffer T, Wetzel C, Kirschner P, Bartosova M, Poth T, Schwab C, Poschet G, Zemva J, Bulkescher R, Damgov I, Thiel C, Garbade SF, Klingbeil K, Peters V, Schmitt CP. Pfeffer T, et al. Among authors: kirschner p. Antioxidants (Basel). 2023 Jun 14;12(6):1270. doi: 10.3390/antiox12061270. Antioxidants (Basel). 2023. PMID: 37372000 Free PMC article.
Identification of myeloid-derived growth factor as a mechanically-induced, growth-promoting angiocrine signal for human hepatocytes.
Große-Segerath L, Follert P, Behnke K, Ettich J, Buschmann T, Kirschner P, Hartwig S, Lehr S, Korf-Klingebiel M, Eberhard D, Lehwald-Tywuschik N, Al-Hasani H, Knoefel WT, Heinrich S, Levkau B, Wollert KC, Scheller J, Lammert E. Große-Segerath L, et al. Among authors: kirschner p. Nat Commun. 2024 Feb 5;15(1):1076. doi: 10.1038/s41467-024-44760-y. Nat Commun. 2024. PMID: 38316785 Free PMC article.
Micro-respirometry of whole cells and isolated mitochondria.
Levitsky Y, Pegouske DJ, Hammer SS, Frantz NL, Fisher KP, Muchnik AB, Saripalli AR, Kirschner P, Bazil JN, Busik JV, Proshlyakov DA. Levitsky Y, et al. Among authors: kirschner p. RSC Adv. 2019;9(57):33257-33267. doi: 10.1039/c9ra05289e. Epub 2019 Oct 17. RSC Adv. 2019. PMID: 32123561 Free PMC article.
Pancreatic islet protection at the expense of secretory function involves serine-linked mitochondrial one-carbon metabolism.
Pelligra A, Mrugala J, Griess K, Kirschner P, Nortmann O, Bartosinska B, Köster A, Krupenko NI, Gebel D, Westhoff P, Steckel B, Eberhard D, Herebian D, Belgardt BF, Schrader J, Weber APM, Krupenko SA, Lammert E. Pelligra A, et al. Among authors: kirschner p. Cell Rep. 2023 Jul 25;42(7):112703. doi: 10.1016/j.celrep.2023.112703. Epub 2023 Jun 22. Cell Rep. 2023. PMID: 37352100 Free PMC article. No abstract available.
Chronic Granulomatous Disease First Diagnosed in Adulthood Presenting With Spinal Cord Infection.
Schwenkenbecher P, Neyazi A, Donnerstag F, Ringshausen FC, Jacobs R, Stoll M, Kirschner P, Länger FP, Valizada E, Gingele S, Wegner F, Sühs KW, Stangel M, Skripuletz T. Schwenkenbecher P, et al. Among authors: kirschner p. Front Immunol. 2018 Jun 4;9:1258. doi: 10.3389/fimmu.2018.01258. eCollection 2018. Front Immunol. 2018. PMID: 29915596 Free PMC article.
Knock-out of dipeptidase CN2 in human proximal tubular cells disrupts dipeptide and amino acid homeostasis and para- and transcellular solute transport.
Pfeffer T, Krug SM, Kracke T, Schürfeld R, Colbatzky F, Kirschner P, Medert R, Freichel M, Schumacher D, Bartosova M, Zarogiannis SG, Muckenthaler MU, Altamura S, Pezer S, Volk N, Schwab C, Duensing S, Fleming T, Heidenreich E, Zschocke J, Hell R, Poschet G, Schmitt CP, Peters V. Pfeffer T, et al. Among authors: kirschner p. Acta Physiol (Oxf). 2024 Apr;240(4):e14126. doi: 10.1111/apha.14126. Epub 2024 Mar 22. Acta Physiol (Oxf). 2024. PMID: 38517248