Preparation of benzalkonium salts differing in the length of a side alkyl chain

Molecules. 2007 Oct 24;12(10):2341-7. doi: 10.3390/12102341.

Abstract

Benzalkonium salts are widely used as disinfectants, biocides and detergents,among a variety of other applications. The cationic surface-activity of these salts determines their potential to act as a biocide on both target and non-target organisms. In this study, a quick synthesis of a complete set of the benzalkonium salts differing in the length of an alkylating chain (from C(2) to C(20)) is described. Moreover, their (1)H-NMR, HPLC-MS, TLC and HPLC analysis were recorded.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Infective Agents, Local / chemical synthesis
  • Anti-Infective Agents, Local / chemistry
  • Benzalkonium Compounds / chemical synthesis*
  • Benzalkonium Compounds / chemistry*
  • Chromatography, High Pressure Liquid
  • Chromatography, Thin Layer
  • Detergents / chemical synthesis
  • Detergents / chemistry
  • Disinfectants / chemical synthesis
  • Disinfectants / chemistry
  • Magnetic Resonance Spectroscopy

Substances

  • Anti-Infective Agents, Local
  • Benzalkonium Compounds
  • Detergents
  • Disinfectants