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Page 1
Toxicity, pharmacokinetics, and effectiveness of the ortho-chlorinated bispyridinium oxime, K870.
Food Chem Toxicol. 2022 Sep;167:113236. doi: 10.1016/j.fct.2022.113236. Epub 2022 Jun 20.
Food Chem Toxicol. 2022.
PMID: 35738326
Acetylcholinesterase Inhibition of Diversely Functionalized Quinolinones for Alzheimer's Disease Therapy.
Bautista-Aguilera ÓM, Ismaili L, Chioua M, Andrys R, Schmidt M, Bzonek P, Martínez-Grau MÁ, Beadle CD, Vetman T, López-Muñoz F, Iriepa I, Refouvelet B, Musilek K, Marco-Contelles J.
Bautista-Aguilera ÓM, et al. Among authors: bzonek p.
Int J Mol Sci. 2020 May 30;21(11):3913. doi: 10.3390/ijms21113913.
Int J Mol Sci. 2020.
PMID: 32486316
Free PMC article.
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In Vitro Evaluation of Oxidative Stress Induced by Oxime Reactivators of Acetylcholinesterase in HepG2 Cells.
Váňová N, Múčková L, Kalíšková T, Lochman L, Bzonek P, Švec F.
Váňová N, et al. Among authors: bzonek p.
Chem Res Toxicol. 2023 Dec 18;36(12):1912-1920. doi: 10.1021/acs.chemrestox.3c00203. Epub 2023 Nov 11.
Chem Res Toxicol. 2023.
PMID: 37950699
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Cysteine-Targeted Insecticides against A. gambiae Acetylcholinesterase Are Neither Selective nor Reversible Inhibitors.
Gorecki L, Andrys R, Schmidt M, Kucera T, Psotka M, Svobodova B, Hrabcova V, Hepnarova V, Bzonek P, Jun D, Kuca K, Korabecny J, Musilek K.
Gorecki L, et al. Among authors: bzonek p.
ACS Med Chem Lett. 2019 Nov 26;11(1):65-71. doi: 10.1021/acsmedchemlett.9b00477. eCollection 2020 Jan 9.
ACS Med Chem Lett. 2019.
PMID: 31938465
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Design and synthesis of novel tacrine-indole hybrids as potential multitarget-directed ligands for the treatment of Alzheimer's disease.
Hamulakova S, Kudlickova Z, Janovec L, Mezencev R, Deckner ZJ, Chernoff YO, Janockova J, Ihnatova V, Bzonek P, Novakova N, Hepnarova V, Hrabinova M, Jun D, Korabecny J, Soukup O, Kuca K.
Hamulakova S, et al. Among authors: bzonek p.
Future Med Chem. 2021 May;13(9):785-804. doi: 10.4155/fmc-2020-0184. Epub 2021 Apr 8.
Future Med Chem. 2021.
PMID: 33829876
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Synthesis, in vitro screening and molecular docking of isoquinolinium-5-carbaldoximes as acetylcholinesterase and butyrylcholinesterase reactivators.
Malinak D, Dolezal R, Hepnarova V, Hozova M, Andrys R, Bzonek P, Racakova V, Korabecny J, Gorecki L, Mezeiova E, Psotka M, Jun D, Kuca K, Musilek K.
Malinak D, et al. Among authors: bzonek p.
J Enzyme Inhib Med Chem. 2020 Dec;35(1):478-488. doi: 10.1080/14756366.2019.1710501.
J Enzyme Inhib Med Chem. 2020.
PMID: 31910701
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Synthesis of New Biscoumarin Derivatives, In Vitro Cholinesterase Inhibition, Molecular Modelling and Antiproliferative Effect in A549 Human Lung Carcinoma Cells.
Hudáčová M, Hamuľaková S, Konkoľová E, Jendželovský R, Vargová J, Ševc J, Fedoročko P, Soukup O, Janočková J, Ihnatova V, Kučera T, Bzonek P, Novakova N, Jun D, Junova L, Korábečný J, Kuča K, Kožurková M.
Hudáčová M, et al. Among authors: bzonek p.
Int J Mol Sci. 2021 Apr 7;22(8):3830. doi: 10.3390/ijms22083830.
Int J Mol Sci. 2021.
PMID: 33917200
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