Tailoring to Search Engines: Bottom-Up Proteomics with Collision Energies Optimized for Identification Confidence.
Révész Á, Milley MG, Nagy K, Szabó D, Kalló G, Csősz É, Vékey K, Drahos L.
Révész Á, et al.
J Proteome Res. 2021 Jan 1;20(1):474-484. doi: 10.1021/acs.jproteome.0c00518. Epub 2020 Dec 7.
J Proteome Res. 2021.
PMID: 33284634
Free PMC article.
We thereby extended our earlier study on Mascot scores and corroborated its findings on the potential bimodal nature of this energy dependence. Optimal energies as a function of m/z show comparable linear trends for the three engines. On the basis of peptide-level results, …
We thereby extended our earlier study on Mascot scores and corroborated its findings on the potential bimodal nature of this energy dependen …