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Application of Physiologically Based Pharmacokinetic Modeling to Predict Drug-Drug Interactions between Elexacaftor/Tezacaftor/Ivacaftor and Tacrolimus in Lung Transplant Recipients.
Pharmaceutics. 2023 May 8;15(5):1438. doi: 10.3390/pharmaceutics15051438.
Pharmaceutics. 2023.
PMID: 37242680
Free PMC article.
Physiologically-Based Pharmacokinetic-Led Guidance for Patients With Cystic Fibrosis Taking Elexacaftor-Tezacaftor-Ivacaftor With Nirmatrelvir-Ritonavir for the Treatment of COVID-19.
Hong E, Almond LM, Chung PS, Rao AP, Beringer PM.
Hong E, et al. Among authors: chung ps.
Clin Pharmacol Ther. 2022 Jun;111(6):1324-1333. doi: 10.1002/cpt.2585. Epub 2022 Apr 6.
Clin Pharmacol Ther. 2022.
PMID: 35292968
Free PMC article.
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Safety of elexacaftor/tezacaftor/ivacaftor dose reduction: Mechanistic exploration through physiologically based pharmacokinetic modeling and a clinical case series.
Hong E, Li R, Shi A, Almond LM, Wang J, Khudari AZ, Haddad S, Sislyan S, Angelich M, Chung PS, Rao AP, Beringer PM.
Hong E, et al. Among authors: chung ps.
Pharmacotherapy. 2023 Apr;43(4):291-299. doi: 10.1002/phar.2786. Epub 2023 Mar 12.
Pharmacotherapy. 2023.
PMID: 36866442
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