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1986 1
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Page 1
A Phase 3, Randomized, Controlled Trial of Resmetirom in NASH with Liver Fibrosis.
Harrison SA, Bedossa P, Guy CD, Schattenberg JM, Loomba R, Taub R, Labriola D, Moussa SE, Neff GW, Rinella ME, Anstee QM, Abdelmalek MF, Younossi Z, Baum SJ, Francque S, Charlton MR, Newsome PN, Lanthier N, Schiefke I, Mangia A, Pericàs JM, Patil R, Sanyal AJ, Noureddin M, Bansal MB, Alkhouri N, Castera L, Rudraraju M, Ratziu V; MAESTRO-NASH Investigators. Harrison SA, et al. N Engl J Med. 2024 Feb 8;390(6):497-509. doi: 10.1056/NEJMoa2309000. N Engl J Med. 2024. PMID: 38324483 Clinical Trial.
A new paradigm for regulatory sciences.
Hilton GM, Bhuller Y, Doe JE, Wolf DC, Currie RA. Hilton GM, et al. Regul Toxicol Pharmacol. 2023 Dec;145:105524. doi: 10.1016/j.yrtph.2023.105524. Epub 2023 Nov 2. Regul Toxicol Pharmacol. 2023. PMID: 37925098 Free article. Review.
Consequently, the issue of rigid legal frameworks has become prominent in global discussions related to the incorporation of reliable and relevant modern technology to fulfill regulatory needs. To explore this issue, we apply Thomas Kuhn's The Structure of Scientific Revol …
Consequently, the issue of rigid legal frameworks has become prominent in global discussions related to the incorporation of reliable and re …
Leg Ulcer Pathway Acceleration (LUPA) study.
Livingstone V, Johnson O, Peta S, Mengtsu A, Quintana B, Moyna C, Hunter C, Thulasidasan N, Black SA. Livingstone V, et al. Br J Surg. 2023 Jun 12;110(7):797-803. doi: 10.1093/bjs/znad088. Br J Surg. 2023. PMID: 37119234
Observation of the peta^{'} Cusp in the New Precise Beam Asymmetry sigma Data for gammappeta.
Afzal F, Wunderlich Y, Anisovich AV, Bayadilov D, Beck R, Becker M, Blanke E, Brinkmann KT, Ciupka S, Crede V, Dieterle M, Dutz H, Elsner D, Friedrich S, Frommberger F, Gridnev A, Gottschall M, Grüner M, Gutz E, Hammann C, Hannappel J, Hartmann J, Hillert W, Hoff J, Hoffmeister P, Honisch C, Jude T, Kalinowsky H, Kalischewski F, Keshelashvili I, Klassen P, Klein F, Klempt E, Koop K, Kroenert P, Krusche B, Lang M, Lopatin I, Mahlberg P, Meißner UG, Messi F, Metag V, Meyer W, Mitlasóczki B, Müller J, Müllers J, Nanova M, Nikonov K, Nikonov V, Novinskiy V, Novotny R, Piontek D, Reicherz G, Richter L, Rönchen D, Rostomyan T, Salisbury B, Sarantsev A, Schaab D, Schmidt C, Schmieden H, Schultes J, Seifen T, Sokhoyan V, Sowa C, Spieker K, Stausberg N, Thiel A, Thoma U, Triffterer T, Urban M, Urff G, van Pee H, Walther D, Wendel C, Wiedner U, Wilson A, Winnebeck A, Witthauer L; CBELSA/TAPS Collaboration. Afzal F, et al. Phys Rev Lett. 2020 Oct 9;125(15):152002. doi: 10.1103/PhysRevLett.125.152002. Phys Rev Lett. 2020. PMID: 33095637
For the first time, a strong cusp effect in a polarization observable has been observed that is an effect of a branch-point singularity at the peta^{'} threshold [E_{gamma}=1447 MeV (W=1896 MeV)]. The latest BnGa partial wave analysis includes the new beam asymmetry data a …
For the first time, a strong cusp effect in a polarization observable has been observed that is an effect of a branch-point singularity at t …
Optical and Thermomechanical Properties of Doped Polyfunctional Acrylate Copolymers.
Hanemann T, Honnef K. Hanemann T, et al. Polymers (Basel). 2018 Mar 19;10(3):337. doi: 10.3390/polym10030337. Polymers (Basel). 2018. PMID: 30966372 Free PMC article.
Three different polyfunctional acrylate monomers-trimethylolpropantriacrylate (TMPTA), pentaerythritol triacrylate (PETA) and di(trimethylolpropane) tetraacrylate (DTTA)-have been used as comonomers in combination with a reactive resin consisting of poly(methylmethacrylate …
Three different polyfunctional acrylate monomers-trimethylolpropantriacrylate (TMPTA), pentaerythritol triacrylate (PETA) and di(trim …
The twin arginine translocation system is essential for aerobic growth and full virulence of Burkholderia thailandensis.
Wagley S, Hemsley C, Thomas R, Moule MG, Vanaporn M, Andreae C, Robinson M, Goldman S, Wren BW, Butler CS, Titball RW. Wagley S, et al. J Bacteriol. 2014 Jan;196(2):407-16. doi: 10.1128/JB.01046-13. Epub 2013 Nov 8. J Bacteriol. 2014. PMID: 24214943 Free PMC article.
In other bacteria, aerobic growth restriction in Tat mutants has been attributed to the inability to translocate PetA, the Rieske iron-sulfur protein which forms part of the quinol-cytochrome c oxidoreductase complex. Here, we show that PetA is not responsible for a …
In other bacteria, aerobic growth restriction in Tat mutants has been attributed to the inability to translocate PetA, the Rieske iro …
Progress towards an OECD reporting framework for transcriptomics and metabolomics in regulatory toxicology.
Harrill JA, Viant MR, Yauk CL, Sachana M, Gant TW, Auerbach SS, Beger RD, Bouhifd M, O'Brien J, Burgoon L, Caiment F, Carpi D, Chen T, Chorley BN, Colbourne J, Corvi R, Debrauwer L, O'Donovan C, Ebbels TMD, Ekman DR, Faulhammer F, Gribaldo L, Hilton GM, Jones SP, Kende A, Lawson TN, Leite SB, Leonards PEG, Luijten M, Martin A, Moussa L, Rudaz S, Schmitz O, Sobanski T, Strauss V, Vaccari M, Vijay V, Weber RJM, Williams AJ, Williams A, Thomas RS, Whelan M. Harrill JA, et al. Regul Toxicol Pharmacol. 2021 Oct;125:105020. doi: 10.1016/j.yrtph.2021.105020. Epub 2021 Jul 29. Regul Toxicol Pharmacol. 2021. PMID: 34333066 Free PMC article.
Sequence of the two operons encoding the four core subunits of the cytochrome b(6)f complex from the thermophilic Cyanobacterium synechococcus elongatus.
Schneider D, Altenfeld U, Thomas H, Schrader S, Mühlenhoff U, Rögner M. Schneider D, et al. Biochim Biophys Acta. 2000 Apr 25;1491(1-3):364-8. doi: 10.1016/s0167-4781(00)00048-8. Biochim Biophys Acta. 2000. PMID: 10760604
The genes encoding cytochrome f (petA), cytochrome b(6) (petB), the Rieske FeS-protein (petC), and subunit IV (petD) of the cytochrome b(6)f complex from the thermophilic cyanobacterium Synechococcus elongatus were cloned and sequenced. Similar to other cyanobacteria, the …
The genes encoding cytochrome f (petA), cytochrome b(6) (petB), the Rieske FeS-protein (petC), and subunit IV (petD) of the cytochrom …
15 results