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Chemical engineering of bacterial effectors for regulating cell signaling and responses.
Yang S, Ngai WSC, Chen PR. Yang S, et al. Curr Opin Chem Biol. 2021 Oct;64:48-56. doi: 10.1016/j.cbpa.2021.04.003. Epub 2021 May 13. Curr Opin Chem Biol. 2021. PMID: 33993047 Review.
We also highlight future opportunities for harnessing diverse prokaryotic effectors as powerful tools for mechanistic investigation and therapeutic intervention of eukaryotic systems....
We also highlight future opportunities for harnessing diverse prokaryotic effectors as powerful tools for mechanistic investigation and t …
Medications, Deep Brain Stimulation, and Other Factors Influencing Impulse Control Disorders in Parkinson's Disease.
Eisinger RS, Ramirez-Zamora A, Carbunaru S, Ptak B, Peng-Chen Z, Okun MS, Gunduz A. Eisinger RS, et al. Front Neurol. 2019 Feb 26;10:86. doi: 10.3389/fneur.2019.00086. eCollection 2019. Front Neurol. 2019. PMID: 30863353 Free PMC article. Review.
In this review, we will summarize the demographic, genetic, behavioral, and clinical contributions potentially influencing ICD onset in PD. These associations may inspire future preventative or therapeutic strategies....
In this review, we will summarize the demographic, genetic, behavioral, and clinical contributions potentially influencing ICD onset in PD. …
Decaging-to-labeling: Development and investigation of quinone methide warhead for protein labeling.
Guo F, Qin S, Liu Z, Chen PR, Fan X. Guo F, et al. Bioorg Chem. 2024 Feb;143:107088. doi: 10.1016/j.bioorg.2023.107088. Epub 2024 Jan 4. Bioorg Chem. 2024. PMID: 38194902
Biomolecule labeling in living systems is crucial for understanding biological processes and discovering therapeutic targets. A variety of labeling warheads have been developed for multiple biological applications, including proteomics, bioimaging, sequencing, and drug dev …
Biomolecule labeling in living systems is crucial for understanding biological processes and discovering therapeutic targets. A varie …