CNVDetector: locating copy number variations using array CGH data

Peng-An Chen; Hsiao-Fei Liu; Kun-Mao Chao

doi:10.1093/bioinformatics/btn517

CNVDetector: locating copy number variations using array CGH data

Bioinformatics. 2008 Dec 1;24(23):2773-5. doi: 10.1093/bioinformatics/btn517. Epub 2008 Oct 7.

Authors

Peng-An Chen¹, Hsiao-Fei Liu, Kun-Mao Chao

Affiliation

¹ Department of Computer Science and Information Engineering, Graduate Institute of Biomedical Electronics and Bioinformatics and Graduate Institute of Networking and Multimedia, National Taiwan University, Taipei, Taiwan.

PMID: 18842603
DOI: 10.1093/bioinformatics/btn517

Abstract

CNVDetector is a program for locating copy number variations (CNVs) in a single genome. CNVDetector has several merits: (i) it can deal with the array comparative genomic hybridization data even if the noise is not normally distributed; (ii) it has a linear time kernel; (iii) its parameters can be easily selected; (iv) it evaluates the statistical significance for each CNV calling.

Availability: CNVDetector (for Windows platform) can be downloaded from http:www.csie.ntu.edu.tw/~kmchao/tools/CNVDetector/. The manual of CNVDetector is also available.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Algorithms*
Comparative Genomic Hybridization / methods*
Gene Dosage
Genetic Variation*
Genome, Human*
Humans
Oligonucleotide Array Sequence Analysis