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Showing results for pan omics
Search for Paz Ovics instead (2 results)
Methods and applications for single-cell and spatial multi-omics.
Vandereyken K, Sifrim A, Thienpont B, Voet T. Vandereyken K, et al. Nat Rev Genet. 2023 Aug;24(8):494-515. doi: 10.1038/s41576-023-00580-2. Epub 2023 Mar 2. Nat Rev Genet. 2023. PMID: 36864178 Free PMC article. Review.
In this Review, we highlight advances in the fast-developing field of single-cell and spatial multi-omics technologies (also known as multimodal omics approaches), and the computational strategies needed to integrate information across these molecular layers. ...
In this Review, we highlight advances in the fast-developing field of single-cell and spatial multi-omics technologies (also known as …
The technological landscape and applications of single-cell multi-omics.
Baysoy A, Bai Z, Satija R, Fan R. Baysoy A, et al. Nat Rev Mol Cell Biol. 2023 Oct;24(10):695-713. doi: 10.1038/s41580-023-00615-w. Epub 2023 Jun 6. Nat Rev Mol Cell Biol. 2023. PMID: 37280296 Free PMC article. Review.
Single-cell multi-omics technologies and methods characterize cell states and activities by simultaneously integrating various single-modality omics methods that profile the transcriptome, genome, epigenome, epitranscriptome, proteome, metabolome and other (emerging …
Single-cell multi-omics technologies and methods characterize cell states and activities by simultaneously integrating various single …
Multi-Omics Profiling for Health.
Babu M, Snyder M. Babu M, et al. Mol Cell Proteomics. 2023 Jun;22(6):100561. doi: 10.1016/j.mcpro.2023.100561. Epub 2023 Apr 27. Mol Cell Proteomics. 2023. PMID: 37119971 Free PMC article. Review.
We will briefly discuss the potential of multi-omics approaches in disentangling host-microbe and host-environmental interactions. We will touch on emerging areas of electronic health record and clinical imaging integration with muti-omics for precision health. Fina …
We will briefly discuss the potential of multi-omics approaches in disentangling host-microbe and host-environmental interactions. We …
Artificial intelligence-based multi-omics analysis fuels cancer precision medicine.
He X, Liu X, Zuo F, Shi H, Jing J. He X, et al. Semin Cancer Biol. 2023 Jan;88:187-200. doi: 10.1016/j.semcancer.2022.12.009. Epub 2022 Dec 31. Semin Cancer Biol. 2023. PMID: 36596352 Review.
A wealth of omics technologies, including bulk and single-cell omics approaches, have empowered to characterize different molecular layers at unprecedented scale and resolution, providing a holistic view of tumor behavior. ...Here, we present state-of-the-art omi …
A wealth of omics technologies, including bulk and single-cell omics approaches, have empowered to characterize different mole …
Integrated Multi-Omics Landscape of Liver Metastases.
Yang S, Qian L, Li Z, Li Y, Bai J, Zheng B, Chen K, Qiu X, Cai G, Wang S, Huang H, Wu J, Zhu Y, Zhangyang Q, Feng L, Wu T, Wu R, Yang A, Wang K, Wang R, Zhang Y, Zhao Y, Wang W, Bao J, Shen S, Hu J, Wu X, Zhou T, Meng Z, Liu W, Wang H, Wang P, Chen L. Yang S, et al. Gastroenterology. 2023 Mar;164(3):407-423.e17. doi: 10.1053/j.gastro.2022.11.029. Epub 2022 Nov 26. Gastroenterology. 2023. PMID: 36574521 Free article.
Furthermore, SLC2A1 promoted immune escape and LM through inducing regulatory T cells, including regulatory T cells and LAG3(+)CD4(+) T cells in primary colorectal cancer. CONCLUSIONS: The study provided integrated multi-omics landscape of LM, uncovering potential mechanis …
Furthermore, SLC2A1 promoted immune escape and LM through inducing regulatory T cells, including regulatory T cells and LAG3(+)CD4(+) T cell …
Insights from multi-omics integration in complex disease primary tissues.
Kreitmaier P, Katsoula G, Zeggini E. Kreitmaier P, et al. Trends Genet. 2023 Jan;39(1):46-58. doi: 10.1016/j.tig.2022.08.005. Epub 2022 Sep 19. Trends Genet. 2023. PMID: 36137835 Free article. Review.
Genome-wide association studies (GWAS) have provided insights into the genetic basis of complex diseases. In the next step, integrative multi-omics approaches can characterize molecular profiles in relevant primary tissues to reveal the mechanisms that underlie disease dev …
Genome-wide association studies (GWAS) have provided insights into the genetic basis of complex diseases. In the next step, integrative mult …
Integration of pan-omics technologies and three-dimensional in vitro tumor models: an approach toward drug discovery and precision medicine.
Jose A, Kulkarni P, Thilakan J, Munisamy M, Malhotra AG, Singh J, Kumar A, Rangnekar VM, Arya N, Rao M. Jose A, et al. Mol Cancer. 2024 Mar 9;23(1):50. doi: 10.1186/s12943-023-01916-6. Mol Cancer. 2024. PMID: 38461268 Free PMC article. Review.
Therefore, there is a need to identify newer and personalized therapeutic targets along with screening technologies to combat cancer. With the advent of pan-omics technologies, such as genomics, transcriptomics, proteomics, metabolomics, and lipidomics, the scientif …
Therefore, there is a need to identify newer and personalized therapeutic targets along with screening technologies to combat cancer. With t …
Pathogenesis, multi-omics research, and clinical treatment of psoriasis.
Yu J, Zhao Q, Wang X, Zhou H, Hu J, Gu L, Hu Y, Zeng F, Zhao F, Yue C, Zhou P, Li G, Li Y, Wu W, Zhou Y, Li J. Yu J, et al. J Autoimmun. 2022 Dec;133:102916. doi: 10.1016/j.jaut.2022.102916. Epub 2022 Oct 6. J Autoimmun. 2022. PMID: 36209691 Review.
In this review, we have discussed the relationship between various types of immune cells and psoriasis and summarized the major signaling pathways involved in the pathogenesis of psoriasis, including the PI3K/AKT/mTOR, JAK-STAT, JNK, and WNT pathways. In addition, we have discuss …
In this review, we have discussed the relationship between various types of immune cells and psoriasis and summarized the major signaling pa …
Pan-cancer analysis from multi-omics data reveals AAMP as an unfavourable prognostic marker.
Wang Y, Liu T, Zhang K, Huang RH, Jiang L. Wang Y, et al. Eur J Med Res. 2023 Jul 27;28(1):258. doi: 10.1186/s40001-023-01234-z. Eur J Med Res. 2023. PMID: 37501187 Free PMC article.
OBJECTIVES: Angio-associated migratory cell protein (AAMP) is a protein that participates in cell migration and is reported to be involved in cancer progression. However, the molecular mechanism of AAMP in pan-cancer is not known. METHODS: We used multi-omics data, …
OBJECTIVES: Angio-associated migratory cell protein (AAMP) is a protein that participates in cell migration and is reported to be involved i …
The Pan-Cancer Multi-Omics Landscape of FOXO Family Relevant to Clinical Outcome and Drug Resistance.
Xie J, Zhang J, Tian W, Zou Y, Tang Y, Zheng S, Wong CW, Deng X, Wu S, Chen J, Mo Y, Xie X. Xie J, et al. Int J Mol Sci. 2022 Dec 9;23(24):15647. doi: 10.3390/ijms232415647. Int J Mol Sci. 2022. PMID: 36555288 Free PMC article.
We calculated the FOXOs score and found that it was significantly correlated with multiple malignant pathways in pan-cancer, including Wnt/beta-catenin signaling, TGF-beta signaling, and hedgehog signaling. ...Furthermore, the FOXOs score was sensitive for predicting the e …
We calculated the FOXOs score and found that it was significantly correlated with multiple malignant pathways in pan-cancer, includin …
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