Vitamin D Supplementation and Its Impact on Different Types of Bone Fractures

Nutrients. 2022 Dec 25;15(1):103. doi: 10.3390/nu15010103.

Abstract

Vitamin D helps to balance the levels of calcium and phosphorus to maintain proper bone structure. It is also involved in essential biological roles and displays a wide spectrum of potential benefits in the human body. Since there are many types of fractures that occur at specific ages and due to different circumstances, the influence of vitamin D on the frequency of a particular fracture may differ. Thus, the authors investigated the possible preventive effect of vitamin D on the risks of vertebral fractures, hip fractures, stress fractures and pediatric fractures. Additional aspects of vitamin D, especially on recuperation after injures and its impact on the severity of particular fractures, were also discussed. It was suggested that vitamin D supplementation may contribute to a reduction in hip fracture risk due to reduced bone turnover, decreased frequency of falls and improved muscle function. Furthermore, vitamin D appears to lower the risk of stress fractures in athletes and military recruits. Due to a nonunified protocol design, presented investigations show inconsistencies between vitamin D supplementation and a decreased risk of vertebral fractures. However, a vitamin D preventive effect on pediatric fractures seems to be implausible.

Keywords: bone fracture; hip fracture; pediatric fracture; stress fracture; vertebral fracture; vitamin D.

MeSH terms

  • Calcium, Dietary
  • Child
  • Dietary Supplements
  • Fractures, Bone* / prevention & control
  • Hip Fractures*
  • Humans
  • Spinal Fractures*
  • Vitamin D
  • Vitamins

Substances

  • Vitamin D
  • Vitamins
  • Calcium, Dietary

Grants and funding

This research received no external funding.